Succinic dehydrogenase activity in human muscle mitochondria during aging: A quantitative cytochemical investigation

Mechanisms of Ageing and Development

Volumn 122, Issue 15, 2001, Pages 1841-1848

  Fattoretti, Patrizia ^a   Vecchiet, Jacopo ^b   Felzani, Giorgio ^b   Gracciotti, Natascia ^a   Solazzi, Moreno ^a   Caselli, Ugo ^a   Bertoni Freddari, Carlo ^a  

^a INRCA   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

Mitochondrial metabolic competence; Mitochondrial plasticity; Morphometry; Muscle aging; Succinic dehydrogenase activity; Succinic dehydrogenase cytochemistry

Indexed keywords

ADENOSINE TRIPHOSPHATE; COPPER; FERROCYANIDE; SUCCINATE DEHYDROGENASE;

ADULT; AGED; AGING; ARTICLE; BIOPSY; CALCULATION; CELL ORGANELLE; CONTROLLED STUDY; CYTOCHEMISTRY; ENERGY; ENZYME ACTIVITY; ENZYME STABILITY; EXCISION; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MALE; MEMBRANE; MODULATION; MORPHOLOGY; MUSCLE MITOCHONDRION; NORMAL HUMAN; ORTHOPEDIC SURGERY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SAMPLE; SARCOMERE; TIBIALIS ANTERIOR MUSCLE; VASTUS LATERALIS MUSCLE;

ADULT; AGED; AGING; HISTOCYTOCHEMISTRY; HUMANS; MIDDLE AGED; MITOCHONDRIA, MUSCLE; SUCCINATE DEHYDROGENASE;

EID: 0034851825     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(01)00320-7     Document Type: Article

References (36)

1. Muscle morphology, enzymatic activity and muscle strength in elderly men: A follow up study
2. Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
3. Morphological plasticity of synaptic mitochondria during aging
4. Age-dependent decrease in the activity of succinic dehydrogenase in rat CA1 pyramidal cells: A quantitative cytochemical study
5. Quantitative cytochemical mapping of mitochondrial enzymes in rat cerebella
6. Metabolic variability within individual fibres of the cat tibialis posterior and diaphragm muscles
7. Decline with age of the respiratory chain activity in human skeletal muscle
8. Mitochondrial function in muscle from elderly athletes
9. mtDNA contributes to neuronal loss in aging
10. Adaptability of the oxidative capacity of motoneurons
11. Age-associated mitochondrial DNA deletions in mouse skeletal muscle: Comparison of different regions of the mitochondrial genome
12. Quantitative cytochemistry of succinic dehydrogenase activity in rat mitochondria
13. Succinic dehydrogenase activity in the aging Purkinje cells: Quantitative ultrastructure of positive mitochondria
14. Morphology and enzymatic capacity in arm and leg muscles in 78-82 year old men and women
15. Modulation of mitochondrial succinate dehydrogenase activity, mechanism of function
16. Electron microscope histochemical evidence for a partial or total block of the tricarboxylic acid cycle in the mitochondria of presynaptic axon terminals
17. Effects of physical training on the metabolism of skeletal muscle
18. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
19. Skeletal muscle atrophy in old rats: Differential changes in the three fiber types
20. Effects of age on the motor unit. A study on single motor units in the rat
21. Multiple mitochondrial DNA deletions associated with age in skeletal muscle of Rhesus monkeys
22. Human aging, muscle mass, and fiber type composition
23. Low succinate dehydrogenase (SDH) activity in a patient with a hereditary myopathy with paroxysmal myoglobinuria
24. Mitochondrial DNA mutations as an important contributor to aging and degenerative diseases
25. Predictable adaptations by skeletal muscle mitochondria to different exercise training workloads
26. Ageing and mammalian mitochondrial genetics
27. Mitochondrial DNA mutation and human aging: Molecular biology, bioenergetics and redox therapy
28. Skeletal muscle metabolism and ultrastructure in relation to age in sedentary men
29. Changes in skeletal muscle with aging: Effects of exercise training
30. Decline in skeletal muscle mitochondrial respiration chain function: Possible factor in aging
31. Strength and aerobic training attenuate muscle wasting and improve resistance to the development of disability with aging
32. Age-dependent modifications of rat heart succinate dehydrogenase
33. A new mtDNA mutation showing accumulation with time and restriction to skeletal muscle
34. Mitochondrial respiratory chain inhibitors induce apoptosis
35. Human skeletal muscle mitochondria in aging: Lack of detectable morphological and enzymic defects