Development of a K562 cell-based assay for screening anticancer agents

Acta Pharmacologica Sinica

Volumn 22, Issue 9, 2001, Pages 821-826

  Qian, J ^a   Zhou, C H ^a   Qian, Z ^a   Nan, F J ^a   Ye, Q Z ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Antineoplastic agents; Antitumor drug screening assays; Cell culture; Drug screening; K562 cells

Indexed keywords

ANTINEOPLASTIC AGENT; ORGANIC COMPOUND;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN K 562; COST EFFECTIVENESS ANALYSIS; DRUG SCREENING; HUMAN; HUMAN CELL;

CELL DIVISION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; K562 CELLS; TETRAZOLIUM SALTS;

EID: 0034849634     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
2. High-throughput screening for human collagenase 1 inhibitors
3. 5-(3-Carboxyl-methophenyl)-2-(4, 5-dimethylthiazolyl)-3-(4-sulfophenyl) tetrazolium, inner salt (MTS) and related analogs of MTT reducing to purple water-soluble formazans as cell-viability indicators
4. Microculture tetrazolium assays: A comparison between two new telrazolium salts, XTT and MTS
5. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay
6. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT
7. New Colorimetric cystoxicity assay for anticancer-drug screening