Is LTP in the hippocampus a useful model for learning-related alterations in gene expression?

Reviews in the Neurosciences

Volumn 12, Issue 3, 2001, Pages 289-296

  Richter Levin, G ^a   Yaniv, D ^a  

^a UNIVERSITY OF HAIFA   (Israel)

Author keywords

Gene expression; Growth factors; Hippocampus; LTP; Memory; MRNA; Signal transduction; Synapse

Indexed keywords

CELL PROTEIN; GROWTH FACTOR;

BRAIN FUNCTION; COMPREHENSION; GENE EXPRESSION; GENE MUTATION; HIPPOCAMPUS; LEARNING; LONG TERM MEMORY; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NERVE FIBER TRANSPORT; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTIC TRANSMISSION;

EID: 0034849621     PISSN: 03341763     EISSN: None     Source Type: Journal    
DOI: 10.1515/REVNEURO.2001.12.3.289     Document Type: Review

References (60)

1. The role of immediate early genes in the stabilization of long-term potentiation
2. Structural changes accompanying memory storage
3. Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
4. Neocortical long-term potentiation
5. A synaptic model of memory: Long-term potentiation in the hippocampus
6. Long-lasting potentiation of synaptic transmission in the dentate area of an anesthetized rabbit following stimulation of the perforant path
7. Unilateral LTP triggers bilateral increases in hippocampal neurotrophin and trk receptor mRNA expression in behaving rats: Evidence for interhemispheric communication
8. LTP, NMDA, genes and learning
9. The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus
10. Synaptic plasticity in fear conditioning circuits: Induction of LTP in the lateral nucleus of the amygdala by stimulation of the medial geniculate body
11. Brain structure and task-specific increase in expression of the gene encoding syntaxin 1B during learning in the rat: A potential molecular marker for learning-induced synaptic plasticity in neural networks
12. Increase in syntaxin 1B mRNA in hippocampal and cortical circuits during spatial learning reflects a mechanism of trans-synaptic plasticity involved in establishing a memory trace
13. Characteristics of hippocampal primed burst potentiation in vitro and in the awake rat
14. A role for immediate early transcription factors in learning and memory
15. Brain-derived neurotrophic factor expression after long-term potentiation
16. TrkB expression in dentate granule cells is associated with a late phase of long-term potentiation
17. Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment
18. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
19. Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro
20. 2+/calmodulin-dependent protein kinase 11 and its endogenous substrates in the induction of long-term potentiation
21. Reciprocal changes in expression of mRNA for nerve growth factor and its receptors TrkA and LNGFR in brain of aged rats in relation to maze learning deficits
22. Increase in syntaxin 1B and glutamate release in mossy fibre terminals following induction of LTP in the dentate gyrus: A candidate molecular mechanism underlying transsynaptic plasticity
23. Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms
24. Synapsin I and syntaxin 1B: Key elements in the control of neurotransmitter release are regulated by neuronal activation and long-term potentiation in vivo
25. Long-lasting forms of synaptic potentiation in the mammalian hippocampus
26. Induction of Fos-like immunoreactivity and the maintenance of long-term potentiation in the dentate gyrus of unanesthetized rats
27. NMDA-dependent induction of long-term potentiation in afferent and association fiber systems of piriform cortex in vitro
28. Storage and release of neurotransmitters
29. Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?
30. Long-term potentiation in the prefrontal cortex following stimulation of the hippocampal CA1/subicular region
31. Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation
32. Relationship of APP mRNA transcripts and levels of NGF and low-affinity NGF receptors to behavioral measures of age-related cognitive dysfunction
33. Increase in synaptic vesicle proteins accompanies long-term potentiation in the dentate gyrus
34. Synaptic plasticity and memory: An evaluation of the hypothesis
35. Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information
36. Cognitive neuroscience and the study of memory
37. Time-dependent changes in neurotrophic factor mRNA expression after kindling and long-term potentiation in rats
38. Synaptic potentiation in the rat dentate gyrus during exploratory learning
39. Potentiation of dentate synapses initiated by exploratory learning in rats: Dissociation from brain temperature, motor activity, and arousal
40. Numerous candidate plasticity-related genes revealed by differential cDNA cloning
41. Requirement of a critical period of transcription for induction of a late phase of LTP
42. Contrasting properties of two forms of long-term potentiation in the hippocampus
43. Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
44. Long-term potentiation in the dentate gyrus is induced preferentially on the positive phase of theta-rhythm
45. Dissociation between genes activated in long-term potentiation and in spatial learning in the rat
46. Changes in hippocampal gene expression associated with the induction of long-term potentiation
47. Long-term potentiation: What's learning got to do with it?
48. Transsynaptic expression of a presynaptic glutamate receptor during hippocampal long-term potentiation
49. Stable hippocampal long-term potentiation elicited by 'theta' pattern stimulation
50. Genetic enhancement of learning and memory in mice
51. Spatial and temporal changes in signal transduction pathways during LTP
52. Alterations in the expression of specific glutamate receptor subunits following hippocampal LTP in vivo
53. Expression of neurotrophin-3 mRNA in the rat visual cortex and hippocampus is influenced by environmental conditions
54. Environmental enrichment results in higher levels of nerve growth factor mRNA in the rat visual cortex and hippocampus
55. Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain
56. Learning-induced alterations in hippocampal PKC-immunoreactivity: A review and hypothesis of its functional significance
57. Immediate early gene transcription and synaptic modulation
58. LTP in the rat basal amygdala induced by perirhinal cortex stimulation, in vivo
59. Decreased NGFI-A gene expression in the hippocampus of cognitively impaired aged rats