Effects of mono-n-butyl phthalate on the development of rat embryos: In vivo and in vitro observations

Pharmacology and Toxicology

Volumn 89, Issue 2, 2001, Pages 104-112

  Saillenfait, Anne Marie ^a   Langonné, Isabelle ^a   Leheup, Bruno ^b  

^a INSTITUT NATIONAL DE RECHERCHE ET DE SÉCURITÉ   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYLTIN DERIVATIVE; PHTHALIC ACID BUTYL ESTER; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DIBUTYL ESTER; PLASTICIZER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MALFORMATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYOTOXICITY; FETUS MALFORMATION; FOREBRAIN; GROWTH RETARDATION; MANDIBLE; MAXILLA; NONHUMAN; PRIORITY JOURNAL; RAT; VISUAL SYSTEM;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; DIBUTYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; ORGAN CULTURE TECHNIQUES; PHTHALIC ACIDS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0034847433     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.2001.890207.x     Document Type: Article

References (6)

1. Albro, P. W. & B. Moore: Identification of the metabolites of simple phthalate diesters in rat urine. J Chromatogr. 1974, 94, 209-218.
2. Cater, B. R., M. K. Cook, S. D. Gangolli & P. Grasso: Studies on dibutyl phthalate-induced testicular atrophy in the rat: Effect on zinc metabolism. Toxicol. Appl. Pharmacol 1977, 41, 609-618.
3. Ema, M., H. Amano, T. Itami & H. Kawasaki: Teratogenic evaluation of di-n-butyl phthalate in rats. Toxicol. Lett. 1993,69, 197-203.
4. Ema, M., H. Amano & Y. Ogawa: Characterization of the developmental toxicity of di-n-butyl phthalate in rats. Toxicology 1994, 86, 163-174.
5. Ema, M., R. Kurosaka, H. Amano & Y. Ogawa: Developmental toxicity evaluation of mono-n-butyl phthalate in rats. Toxicol. Lett. 1995a, 78, 101-106.
6. Erna, M., R. Kurosaka & Y. Ogawa: Comparative developmental toxicity of n-butyl benzyl phthalate and di-n-butyl phthalate in rats. Arch. Environ. Contain. Toxicol. 1995b, 28, 223-228.