Effects of ACE inhibition and angiotensin II type 1 receptor blockade on cardiac function and G proteins in rats with chronic heart failure

British Journal of Pharmacology

Volumn 134, Issue 1, 2001, Pages 150-160

  Yoshida, H ^a   Takahashi, M ^a   Tanonaka, K ^a   Maki, T ^a   Nasa, Y ^a   Takeo, S ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Cardiac fibrosis; Collagen; G proteins; L 158809; Trandolapril

Indexed keywords

2 ETHYL 5,7 DIMETHYL 3 [4 [2 (2H TETRAZOL 5 YL)PHENYL]BENZYL]IMIDAZO[4,5 B]PYRIDINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; TRANDOLAPRIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRUG EFFECT; ENZYME INHIBITION; FIBROBLAST CULTURE; HEART FAILURE; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE FIBROSIS; HEMODYNAMICS; LONG TERM CARE; MALE; NONHUMAN; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0034846206     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704219     Document Type: Article

References (39)

1. Enhanced expression of inhibitory guanine nucleotide regulatory protein in spontaneously hypertensive rats
2. Effects of angiotensin II type 1 receptor blockade and angiotensin-converting enzyme inhibition on cardiac β-adrenergic signal transduction
3. Alternative pathways of angiotensin II production in the human saphenous vein
4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
5. Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction: Effects on systolic function
6. Plasma norepinephrine, plasma renin activity, and congestive heart failure. Relations to survival and the effects of therapy in V-HeFT II
7. Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: Evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes
8. Effects of captopril on myocardial β-adrenoceptor density and Giα-proteins in patients with mild to moderate heart failure due to dilated cardiomyopathy
9. qα and PLC-β in scar and border tissue in heart failure due to myocardial infarction
10. Angiotensin II mediates drinking elicited by eating in the rat
11. Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro
12. 1-adrenergic stimulation
13. The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence
14. Effects of angiotensin-converting enzyme inhibitors and angiotensin II type I receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors
15. A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections
16. Effect of neutral endopeptidase inhibitor on endogenous atrial natriuretic peptide as a paracrine factor in cultured cardiac fibroblasts
17. Comparison of candesartan, enalapril, and their combination in congestive heart failure: Randomized evaluation of strategies for left ventricular dysfunction (RESOLVED) pilot study. The RESOLVD Pilot Study Investigators
18. Developmental changes of the G proteins-muscarinic cholinergic receptor interactions in rat heart
19. Mechanisms and implications of autonomic nervous system dysfunction in heart failure
20. Role of chymase on vascular proliferation
21. sα in myofibroblasts localized to the infarct scar in heart failure due to myocardial infarction
22. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators
23. Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE)
24. 2+-dependent signaling
25. Long-term treatment with angiotensin I-converting enzyme inhibitors attenuates the loss of cardiac beta-adrenoceptor responses in rats with chronic heart failure
26. Regional energy metabolism of failing hearts following myocardial infarction
27. i-2 levels in rat hearts associated with impaired heart function after myocardial infarction
28. Local renin-angiotensin systems in cardiovascular tissues: Localization and functional role
29. Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
30. Effects of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure
31. Regulation of cardiac L-type calcium current by phosphorylation and G proteins
32. Angiotensin II-forming pathways in normal and failing human hearts
33. Identification of functional angiotensin II receptors on rat cardiac fibroblasts
34. Extracellular matrix remodeling in heart failure: A role of de novo Angiotensin II generation
35. Collagen network of the myocardium: Function, structural remodeling and regulatory mechanisms
36. Functional and biochemical analysis of angiotensin II-forming pathways in the human heart
37. Three-dimensional molecular modeling explains why catalytic function for angiotensin-I is different between human and rat chymases
38. Characterization of cardiac myocyte and tissue β-adrenergic signal transduction in rats with heart failure
39. Cell type-specific angiotensin II-evoked signal transduction pathways: Critical roles of Gβγ subunit, Src family, and Ras in cardiac fibroblasts