DNA topology on an increase in positive writhing number of DNA: Conformation changes in the time course of cis-diamminedichloroplatinum(II)-DNA adducts

Chemical and Pharmaceutical Bulletin

Volumn 49, Issue 9, 2001, Pages 1053-1060

  Kobayashi, S ^a   Nakamura, Y ^a   Maehara, T ^a   Hamashima, H ^a   Sasatsu, M ^a   Asano, K ^a   Ohishi, Y ^a   Tanaka, A ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Anticancer therapy; cis diamminedichloroplatinum(II); DNA topology; Gel electrophoresis; White rule; Writhing number

Indexed keywords

CISPLATIN; DNA;

ARTICLE; COMPLEX FORMATION; CROSS LINKING; DNA ADDUCT; DNA CONFORMATION; DRUG BINDING; DRUG DNA BINDING; ELECTRON MICROSCOPY; GEL MOBILITY SHIFT ASSAY; METHODOLOGY; MOBILIZATION; REACTION TIME; THERMODYNAMICS; WRITHING TEST;

ALGORITHMS; ANTINEOPLASTIC AGENTS; CISPLATIN; CYANIDES; DNA; DNA ADDUCTS; DNA, SUPERHELICAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GUANINE; MICROSCOPY, ELECTRON; NUCLEIC ACID CONFORMATION; PLATINUM; STEREOISOMERISM;

EID: 0034843346     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.49.1053     Document Type: Article

References (18)