Matrilins: Structure, expression and function

Osteoarthritis and Cartilage

Volumn 9, Issue SUPPL. A, 2001, Pages

  Segat, D ^a   Paulsson, M ^a   Smyth, N ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; COLLAGEN TYPE 6; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; MATRILIN; MATRILIN 1; MATRILIN 2; MATRILIN 3; MATRILIN 4; MESSENGER RNA; PROTEIN PRECURSOR; SCLEROPROTEIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL MATURATION; CHICKEN; CHONDROGENESIS; CHROMOSOME 1; CONTROLLED STUDY; DISEASE MARKER; EMBRYO; FIBROBLAST; GENE EXPRESSION; GENETIC REGULATION; GROWTH PLATE; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; LIMB DEVELOPMENT; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYCHONDRITIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RADIOIMMUNOASSAY; RHEUMATOID ARTHRITIS; SILENCER GENE;

EID: 0034842969     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1053/joca.2001.0441     Document Type: Article

References (52)

1. Matrix proteins bound to associatively prepared proteoglycans from bovine cartilage
2. Radioimmunoassay of the 148 kilodalton cartilage protein; distribution of the protein among bovine tissues
3. Primary structure and expression of matrilin-2, the closest relative of cartilage matrix protein within the von Willebrand factor type A-like module superfamily
4. Primary structure of matrilin-3, a new member of a family of extracellular matrix proteins related to cartilage matrix protein (matrilin-1) and von Willebrand factor
5. Matrilin-3 from chicken cartilage
6. Matrilin-4, a new member of the matrilin family of extracellular matrix proteins
7. Molecular structure, processing and tissue distribution of matrilin-4
8. Matrilin-3 forms disulfide-linked oligomers with matrilin-1 in bovine epiphyseal cartilage
9. Molecular structure and tissue distribution of matrilin-3, a filament-forming extracellular matrix protein expressed during skeletal development
10. The matrilins: A novel family of oligomeric extracellular matrix proteins
11. Purification and structural characterization of a cartilage matrix protein
12. Structural features of cartilage matrix protein deduced from cDNA
13. Structure of the gene for cartilage matrix protein, a modular protein of the extracellular matrix. Exon intron organization, unusual splice sites, and relation to α-chains of β2 integrins, von Willebrand Factor, and factor-C2, and epidermal growth factor
14. Structure and chromosomal location of the human gene encoding cartilage matrix protein
15. Cloning, sequencing and expression analysis of mouse cartilage matrix protein cDNA
16. Native cartilage matrix protein (CMP). A compact trimer of subunits assembled via a coiled-coil a-helix
17. The role of coiled-coil alpha-helices and disulfide bonds in the assembly and stabilization of cartilage matrix protein subunits. A mutational analysis
18. Heteronuclear NMR assignments and secondary structure of the coiled coil trimerization domain from cartilage matrix protein in oxidized and reduced forms
19. Sequence, structure and chromosomal localization of Crtm gene encoding mouse cartilage matrix protein and its exclusion as a candidate for murine achondroplasia
20. Identification of positive and negative regulatory regions controlling expression of the cartilage matrix protein gene
21. Identification of a nuclear factor-I family protein-binding site in the silencer region of the cartilage matrix protein gene
22. The zonal expression of chicken cartilage matrix protein gene in the developing skeleton of transgenic mice
23. Variation in quantity and extractability of the 148-kilodalton cartilage protein with age
24. Gene regulation during cartilage differentiation: Temporal and spatial expression of link protein and cartilage matrix protein in the developing limb
25. Evidence for sequential appearance of cartilage matrix proteins in developing mouse limbs and in cultures of mouse mesenchymal cells
26. Type VI collagen expression is upregulated in the early events of chondrocyte differentiation
27. Expression of the cartilage matrix protein gene at different chondrocyte developmental stages
28. Progression and recapitulation of the chondrocyte differentiation program: Cartilage matrix protein is a marker for cartilage maturation
29. A short chain (pro)collagen from aged endochondral chondrocytes; biochemical characterization
30. Developmental expression of human cartilage matrix protein
31. Involvement of nonarticular cartilage, as demonstrated by release of a cartilage-specific protein, in rheumatoid arthritis
32. Serum concentrations of two cartilage matrix proteins reflecting different aspects of cartilage turnover in relapsing polychondritis
33. Enhancement of cartilage matrix protein synthesis in arthritic cartilage
34. The spatial and temporal expression pattern of cartilage matrix protein illustrates the molecular heterogeneity of cartilage
35. Cartilage matrix protein forms a type II collagen-independent filamentous network: Analysis in primary cell cultures with a retrovirus expression system
36. Expression of cartilage-matrix genes and localization of their translation products in the embryonic chick eye
37. Expression of matrilin-1, -2 and -3 in developing mouse limbs and heart
38. The C-terminal domain of cartilage matrix protein assembles into a triple-stranded a-helical coiled-coil structure
39. NMR structure of a parallel homotrimeric coiled coil
40. Interaction of cartilage matrix protein with aggrecan. Increased covalent cross-linking with tissue maturation
41. Cartilage matrix protein is a component of the collagen fibril of cartilage
42. Assembly of a novel cartilage matrix protein filamentous network: Molecular basis of differential requirement of von Willebrand factor A domains
43. Oligomeric forms of the 148 kDa cartilage matrix protein
44. Primary structure of human matrilin-2, chromosome location of the MATN2 gene and conservation of an AT-AC intron in matrilin genes
45. The C-terminal domain of matrilin-2 assembles into a three-stranded α-helical coiled coil
46. Matrilin-2, a large oligomeric matrix protein, is expressed by a great variety of cells and forms fibrillar networks
47. Characterization of human matrilin-3 (MATN3)
48. Structure and mapping of the mouse matrilin-3 gene (Matn3), a member of a gene family containing a U12-type AT-AC intron
49. Genomic organisation, alternative splicing and primary structure of human matrilin-4
50. Enhancement of cell adhesion and spreading by a cartilage-specific noncollagenous protein, cartilage matrix protein (CMP/matrilin-1), via integrin α1β1
51. Normal skeletal development of mice lacking matrilin 1: Redundant function of matrilins in cartilage?
52. Mice lacking matrilin-1 (cartilage matrix protein) have alterations in type II collagen fibrillogenesis and fibril organization