Malignant hyperthermia and excitation-contraction coupling

Acta Physiologica Scandinavica

Volumn 171, Issue 3, 2001, Pages 367-378

  Melzer, W ^a   Dietze, B ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Calcium channel; Calcium release; Dihydropyridine receptor; Excitation contraction coupling; Malignant hyperthermia; Muscle disease; Ryanodine receptor; Skeletal muscle

Indexed keywords

1,4 DIHYDROPYRIDINE RECEPTOR; ANESTHETIC AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; RYANODINE RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; CALCIUM TRANSPORT; CONFERENCE PAPER; EXCITATION CONTRACTION COUPLING; GENE MUTATION; GENERAL ANESTHESIA; GENETIC PREDISPOSITION; HUMAN; HUMAN CELL; MALIGNANT HYPERTHERMIA; MEMBRANE DEPOLARIZATION; MUSCLE METABOLISM; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; SWINE; VOLTAGE CLAMP;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; DISEASE MODELS, ANIMAL; HUMANS; MALIGNANT HYPERTHERMIA; MUSCLE CONTRACTION; MUSCLE, SKELETAL; MUTATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SWINE;

EID: 0034840477     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2001.00840.x     Document Type: Conference Paper

References (120)

1. Excitation-contraction coupling produced by a skeletal muscle dihydropyridine receptor α1S subunit lacking the II-III loop
2. Functional impact of the ryanodine receptor on the skeletal muscle L-type Ca(2+) channel
3. Modulation of the sarcolemmal L-type current by alteration in SR Ca2+ release
4. Sarcoplasmic reticulum calcium release in frog skeletal muscle fibres estimated from Arsenazo III calcium transients
5. A lethal mutation in mice eliminates the slow calcium current in skeletal muscle cells
6. Calcium ion in skeletal muscle: Its crucial role for muscle function, plasticity, and disease
7. Involvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscle
8. The voltage sensor in voltage-dependent ion channels
9. Structural evidence for direct interaction between the molecular components of the transverse tubule/sarcoplasmic reticulum junction in skeletal muscle
10. A novel ryanodine receptor mutation and genotype-phenotype correlation in a large malignant hyperthermia New Zealand Maori pedigree
11. Intracellular calcium homeostasis in human primary muscle cells from malignant hyperthermia-susceptible and normal individuals. Effect of overexpression of recombinant wild-type and Arg163Cys mutated ryanodine receptors
12. A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice
13. Molecular identification of the ryanodine receptor Ca2+ sensor
14. Depolarization-induced calcium release from isolated triads measured with impermeant fura-2
15. Interfering with calcium release suppresses I gamma, the 'hump' component of intramembranous charge movement in skeletal muscle
16. Microinjection of strong calcium buffers suppresses the peak of calcium release during depolarization in frog skeletal muscle fibers
17. Excitation-calcium release uncoupling in aged single human skeletal muscle fibers
18. Voltage-controlled Ca2+ release in normal and ryanodine receptor type 3 (RyR3)-deficient mouse myotubes
19. Malignant hyperthermia mutation Arg615Cys in the porcine ryanodine receptor alters voltage dependence of Ca2+ release
20. Role of calcium permeation in dihydropyridine receptor function. Insights into channel gating and excitation-contraction coupling
21. Ca(2+) inactivation sites are located in the COOH-terminal quarter of recombinant rabbit skeletal muscle Ca(2+) release channels (ryanodine receptors)
22. Mutation of divergent region 1 alters caffeine and Ca(2+) sensitivity of the skeletal muscle Ca(2+) release channel (ryanodine receptor)
23. Identification of calcium release-triggering and blocking regions of the II-III loop of the skeletal muscle dihydropyridine receptor
24. A possible role of sarcoplasmic Ca2+ release in modulating the slow Ca2+ current of skeletal muscle
25. Abnormal ryanodine receptor channels in malignant hyperthermia
26. Absence of Ca2+ current facilitation in skeletal muscle of transgenic mice lacking the type 1 ryanodine receptor
27. Studies of the triad. 3. Structure of the junction in fast twitch fibers
28. Membrane particles and transmission at the triad
29. Alternate disposition of tetrads in peripheral couplings of skeletal muscle
30. Ryanodine receptors of striated muscles: A complex channel capable of multiple interactions
31. Shape, size, and distribution of Ca(2+) release units and couplons in skeletal and cardiac muscles
32. Absence of the gamma subunit of the skeletal muscle dihydropyridine receptor increases L-type Ca2+ currents and alters channel inactivation properties
33. Cellular membrane potentials and contractile threshold in mammalian skeletal muscle susceptible to malignant hyperthermia
34. Skeletal muscle excitation-contraction coupling. II. Plasmalemma voltage control of intact bundle contractile properties in normal and malignant hyperthermic muscles
35. Excitation-contraction coupling in pigs heterozygous for malignant hyperthermia
36. Porcine malignant hyperthermia: Genotype and contractile threshold of immature muscles
37. Slow calcium current is not reduced in malignant hyperthermic porcine myotubes
38. Calcium transients and calcium release in rat fast-twitch skeletal muscle fibres
39. Measurement of calcium transients and slow calcium current in myotubes
40. The II-III loop of the skeletal muscle dihydropyridine receptor is responsible for the bi-directional coupling with the ryanodine receptor
41. Absence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha 1 subunit and eliminates excitation-contraction coupling
42. Malignant hyperthermia
43. Caffeine and excitation-contraction coupling in skeletal muscle: A stimulating story
44. A new twist in the saga of charge movement in voltage-dependent ion channels
45. Contribution of a voltage-sensitive calcium release mechanism to contraction in cardiac ventricular myocytes
46. Intramembrane charge movements in skeletal muscle
47. Chemical depolarization-induced SR calcium release in triads isolated from rabbit skeletal muscle
48. Low myoplasmic Hg2+ potentiates calcium release during depolarization of frog skeletal muscle fibers
49. Reduction of calcium inactivation of sarcoplasmic reticulum calcium release by fura-2 in voltage-clamped cut twitch fibers from frog muscle
50. Effect of sarcoplasmic reticulum calcium depletion on intramembranous charge movement in frog cut muscle fibers
51. III-IV loop of cardiac L-type calcium channel contributes to fast inactivation as impiled by a naturally occuring disease-causing mutation
52. Genetics and pathogenesis of malignant hyperthermia
53. Voltage dependence of the pattern and frequency of discrete Ca2+ release events after brief repriming in frog skeletal muscle
54. Repriming and activation alter the frequency of stereotyped discrete Ca2+ release events in frog skeletal muscle
55. Modulation of the frequency of spontaneous sarcoplasmic reticulum Ca2+ release events (Ca2+ sparks) by myoplasmic [Mg2+] in frog skeletal muscle
56. Calcium release in skinned muscle fibres of the toad by transverse tubule depolarization or by direct stimulation
57. Effect of Mg2+ on the control of Ca2+ release in skeletal muscle fibres of the toad
58. Excitation-contraction coupling and fatigue in skeletal muscle
59. Excitation-contraction coupling in skeletal muscle: Comparisons with cardiac muscle
60. Magnesium inhibition of ryanodine-receptor calcium channels: Evidence for two independent mechanisms
61. Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia
62. Inactivation of Ca2+ release channels (ryanodine receptors RyR1 and RyR2) with rapid steps in [Ca2+] and voltage
63. A 37-amino acid sequence in the skeletal muscle ryanodine receptor interacts with the cytoplasmic loop between domains II and III in the skeletal muscle dihydropyridine receptor
64. The cytoplasmic loops between domains II and III and domains III and IV in the skeletal muscle dihydropyridine receptor bind to a contiguous site in the skeletal muscle ryanodine receptor
65. Malignant hyperthermia and central core disease: Disorders of Ca2+ release channels
66. Activation of the skeletal muscle calcium release channel by a cytoplasmic loop of the dihydropyridine receptor
67. A mutation in the transmembrane/luminal domain of the ryanodine receptor is associated with abnormal Ca2+ release channel function and severe central core disease
68. Protein-protein interactions in intracellular Ca2+-release channel function
69. Malignant hyperthermia
70. Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscle
71. Coupled gating between individual skeletal muscle Ca2+ release channels
72. Ryanodine receptor mutations in malignant hyperthermia and central core disease
73. Regulation of skeletal muscle Ca2+ release channel (ryanodine receptor) by Ca2+ and monovalent cations and anions
74. Time course of calcium release and removal in skeletal muscle fibers
75. A general procedure for determining the rate of calcium release from the sarcoplasmic reticulum in skeletal muscle fibers
76. The role of Ca2+ ions in excitation-contraction coupling of skeletal muscle fibres
77. Abnormal sarcoplasmic reticulum ryanodine receptor in malignant hyperthermia
78. Malignant hyperthermia: Excitation-contraction coupling, Ca2+ release channel, and cell Ca2+ regulation defects
79. Malignant-hyperthermia susceptibility is associated with a mutation of the alpha 1-subunit of the human dihydropyridine-sensitive L-type voltage-dependent calcium-channel receptor in skeletal muscle
80. Role of Mg(2+) in Ca(2+)-induced Ca(2+) release through ryanodine receptors of frog skeletal muscle: Modulations by adenine nucleotides and caffeine
81. Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor
82. Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels
83. Role of RyR1 residues 1837-2154 in reciprocal communication with α1s
84. Calmodulin sensitivity of the sarcoplasmic reticulum ryanodine receptor from normal and malignant-hyperthermia-susceptible muscle
85. Calcium-induced Ca2+ release from sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia. The effects of halothane and dantrolene
86. FKBP12 modulates gating of the ryanodine receptor/calcium release channel
87. Two structural configurations of the skeletal muscle calcium release channel
88. The point mutation Arg615->Cys in the Ca2+ release channel of skeletal sarcoplasmic reticulum is responsible for hypersensitivity to caffeine and halothane in malignant hyperthermia
89. Coordinated incorporation of skeletal muscle dihydropyridine receptors and ryanodine receptors in peripheral couplings of BC3H1 cells
90. Cryoelectron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle
91. Functional characterization of a distinct ryanodine receptor mutation in human malignant hyperthermia-susceptible muscle
92. Voltage sensor of excitation-contraction coupling in skeletal muscle
93. Charge movement and the nature of signal transduction in skeletal muscle excitation-contraction coupling
94. Calcium in close quarters: Microdomain feedback in excitation-contraction coupling and other cell biological phenomena
95. Screening of the ryanodine receptor gene and identification of novel mutations in North American malignant hyperthermia population
96. Inactivation of calcium release from the sarcoplasmic reticulum in frog skeletal muscle
97. Control of calcium release in functioning skeletal muscle fibers
98. Ca2+ sparks in frog skeletal muscle: Generation by one, some, or many SR Ca2+ release channels?
99. Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel
100. Inactivation of gating currents of L-type calcium channels. Specific role of the alpha 2 delta subunit
101. Ca2+ release from the sarcoplasmic reticulum compared in amphibian and mammalian skeletal muscle
102. Local calcium release in mammalian skeletal muscle
103. Calcium sparks: Release packets of uncertain origin and fundamental role
104. Reconstitution of abnormalities in the malignant hyperthermia-susceptible pig ryanodine receptor
105. The structure, function, and cellular regulation of ryanodine-sensitive Ca2+ release channels
106. Effects of the dihydropyridine receptor subunits gamma and alpha2delta on the kinetics of heterologously expressed L-type Ca2+ channels
107. Events of the excitation-contraction-relaxation (E-C-R) cycle in fast- and slow-twitch mammalian muscle fibres relevant to muscle fatigue
108. Local control model of excitation-contraction coupling in skeletal muscle
109. Triadic Ca2+ modulates charge movement in skeletal muscle
110. Voltage-dependent calcium release in human malignant hyperthermia muscle fibers
111. Ryanodine receptor Ca2+ release channels: Does diversity in form equal diversity in function?
112. Restoration of junctional tetrads in dysgenic myotubes by dihydropyridine receptor cDNA
113. Co-expression in CHO cells of two muscle proteins involved in excitation-contraction coupling
114. Regions of the skeletal muscle dihydropyridine receptor critical for excitation-contraction coupling
115. Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics
116. Caffeine and halothane sensitivity of intracellular Ca2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease
117. Calmodulin activation and inhibition of skeletal muscle Ca2+ release channel (ryanodine receptor)
118. Excitation-contraction coupling in skeletal muscle of a mouse lacking the DHP receptor subunit gamma1
119. Locations of calmodulin and FK506-binding protein on the three-dimensional architecture of the skeletal muscle ryanodine receptor
120. Subunit interaction sites in voltage-dependent Ca2+ channels: Role in channel function