Dual colour FISH in paraffin wax embedded bone trephines for identification of numerical and structural chromosomal abnormalities in acute myeloid leukaemia and myelodysplasia

Journal of Clinical Pathology

Volumn 54, Issue 9, 2001, Pages 730-733

  Le Maitre, C L ^a   Byers, R J ^a   Liu Yin, J A ^b   Hoyland, J A ^a   Freemont, A J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Acute myeloid leukaemia; Cytogenetic abnormalities; Fluorescence in situ hybridisation; Myelodysplasia; Paraffin wax embedded bone trephines

Indexed keywords

AVIDIN; DIGOXIGENIN; ISOTHIOCYANIC ACID; PARAFFIN; RHODAMINE;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CHROMOSOME 8; CHROMOSOME TRANSLOCATION; CLINICAL PRACTICE; CONTROLLED STUDY; CYTOGENETICS; FEMALE; FILTER; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; LABORATORY TEST; MALE; MYELODYSPLASIA; NUMERICAL CHROMOSOME ABERRATION; PRIORITY JOURNAL; STRUCTURAL CHROMOSOME ABERRATION; TRISOMY 8;

EID: 0034839841     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.54.9.730     Document Type: Article

References (10)

1. Histopathology of myelodysplastic syndromes (MDS): Application of FAB proposals to plastic embedded bone-marrow biopsy
2. Bone marrow histology in the myelodysplastic syndromes II. Prognostic value of abnormal localisation of immature precursors in MDS
3. Life expectancy in primary myelodyspalstic syndromes: A prognostic score based upon histopathology from bone marrow biopsies of 569 patients
4. Abnormal localisation of immature precursors (ALIP) in the bone marrow of myelodysplastic syndromes: Current state of knowledge and future directions
5. Interphase cytogenetics and pathology: A tool for diagnosis and research
6. Fluorescence in-situ hybridisation (FISH) reveals that in chronic myelogenous leukaemia (CML) following interferon-alpha therapy, normalisation of megakaryocyte size is associated with loss of the bca/abl translocation
7. Chromosome translocations in sarcomas and the analysis of paraffin-embedded material
8. Demonstration of the Philadelphia translocation by fluorescence in situ hybridisation (FISH) in paraffin sections and identification of aberrant cells by a combined FISH/immunophenotyping approach
9. Rapid detection of karyrope changes in interphase bone marrow cells by oligonucleotide primed in situ hybridisation (PRINS)
10. Assessment of intra-tumoral karyotypic heterogeneity by interphase cyrogenetics in paraffin wax sections