Phylogenetic diversity and similarity of active sites of Shiga toxin (Stx) in Shiga toxin-producing Escherichia coli (STEC) isolates from humans and animals

Epidemiology and Infection

Volumn 127, Issue 1, 2001, Pages 27-36

  Asakura, H ^a   Makino, S I ^a   Kobori, H ^a   Watarai, M ^a   Shirahata, T ^a   Ikeda, T ^b   Takeshi, K ^b  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^b HOKKAIDO INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SHIGA TOXIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BACTERIUM ISOLATE; CATTLE; CONTROLLED STUDY; CYTOTOXICITY; DEER; ESCHERICHIA COLI; FLY; GENETIC ANALYSIS; GENETIC VARIABILITY; HOST; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHYLOGENY; SHEEP;

AMINO ACID SEQUENCE; ANIMALS; DATABASES, FACTUAL; ESCHERICHIA COLI; HUMANS; PHYLOGENY; SHIGA TOXIN; VARIATION (GENETICS);

EID: 0034839537     PISSN: 09502688     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0950268801005635     Document Type: Article

References (56)

1. The epidemiology of infections caused by Escherichia coli, other enterohemorrhagic E. coli, and the associated hemolytic uremic syndrome
2. Zoonotic Non-O157 Shiga Toxin-Producing Escherichia coli (STEC)
3. Which Shiga toxin-producing types of E. coli are important?
4. Infection by verocytotoxin-producing Escherichia coli
5. Virulence markers of Shiga-like toxin-producing Escherichia coli strains originating from healthy domestic animals of different species
6. Characterization of Escherichia coli O157:H7 and other shiga toxin-producing E. coli serotypes isolated from sheep
7. Detection and characterization of fecal Verocytotoxin-producing Escherichia coli from healthy cattle
8. Verotoxigenic E. coli O157 colonization of wild deer and range cattle
9. Isolation of Verocytotoxin-producing Escherichia coli from cattle and pets
10. Cloning and nucleotide sequence analysis of the genes determining verocytotoxin production in a porcine edema disease isolate of Escherichia coli
11. Pathogenesis and diagnosis of Shiga toxin-producing Escherichia coli infections
12. Cloning and sequencing of a shiga-like toxin type II variant from an Escherichia coli strain responsible for edema disease of swine
13. Abundance in sewage of bacteriophages that infect Escherichia coli O157:H7 and that carry the Shiga toxin 2 gene
14. Occurrence of phages infecting Escherichia coli O157:H7 carrying the Stx2 gene in sewage from different countries
15. Detection and long-term existence of Shiga toxin (Stx)-producing Escherichia coli in sheep
16. Detection and genetical characterization of Shiga toxin-producing Escherichia coli from wild deer
17. Detection and characterization of Shiga toxin-producing Escherichia coli from seagulls
18. Detection of Escherichia coli O157:H7 from Musca domestica (Diptera: Muscidae) at a cattle farm in Japan
19. Typing of verotoxins by DNA colony hybridization with poly- and oligonucleotide probes, a bead-enzyme-linked immunoorbent assay, and polymerase chain reaction
20. Nucleotide sequence of the Shiga-like toxin genes of Escherichia coli
21. Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coli
22. The primary structure of the operons coding for Shigella dysenteriae toxin and temperate phage H30 shiga-like toxin
23. Sequence of a variant Shiga-like toxin type-I operon of Escherichia coli O111:H-
24. Heterogeneity of the amino-acid sequences of Escherichia coli Shiga-like toxin type-I operons
25. Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages from Escherichia coli
26. Cloning and nucleotide sequence analysis of verotoxin gene from Escherichia coli O157 KNIH317 isolated in Korea
27. Polymerase chain reaction amplification, cloning and sequencing of variant Escherichia coli Shiga-like toxin type II operons
28. Two copies of Shiga-like toxin II-related genes common in enterohemorrhagic Escherichia coli strains are responsible for the antigenic heterogeneity of the O157:H- strain E32511
29. Cloning and sequencing of a Shiga-like toxin II-related gene from Escherichia coli O157:H7 strain 7279
30. Comparative toxicity and virulence of Escherichia coli clones expressing variant and chimeric Shiga-like toxin type II operons
31. Enterohemorrhagic Escherichia coli O157 outbreak in Obihiro city. Biological and molecular characteristics among O157 isolates
32. Identification of an insertion sequence, IS1203 variant, in a Shiga toxin 2 gene of Escherichia coli O157:H7
33. Identification of new verocytotoxin type 2 variant B-subunit genes in human and animal Escherichia coli isolates
34. Cloning and nucleotide sequence of a variant Shiga-like toxin II gene from Escherichia coli OX3:H21 isolated from a case of sudden infant death syndrome
35. Study on the verotoxin-producing Escherichia coli-isolation of the bacteria from deer dung
36. Clonal relatedness of Shiga-like toxin producing Escherichia coli O101 strains of human and porcine origin
37. Cloning and sequence analysis of another Shiga-like toxin IIe variant gene (slt-IIera) from an Escherichia coli R107 strain isolated from rabbit
38. A new shiga toxin 2 variant (Stx2f) from Escherichia coli isolated from pigeons
39. Molecular cloning and nucleotide sequence of another variant of the Escherichia coli Shiga-like toxin II family
40. Mutations affecting the activity of the Shiga-like toxin IA-chain
41. The role of tyrosine-114 in the enzymatic activity of Shiga-like toxin 1A-chain
42. Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I
43. Importance of arginine at position 170 of the A subunit of Vero toxin produced by enterohemorrhagic Escherichia coli for toxin activity
44. Characterization of non-toxic mutant toxins of Verotoxin I that were constructed by replacing amino acids in the A subunit
45. Construction of mutant genes for a non-toxic verotoxin 2 variant (VT2vp1) of Escherichia coli and characterization of purified mutant toxins
46. Verotoxins and their glycolipid receptors
47. Role of verotoxin receptors in pathogenesis
48. Alteration of the carbohydrate binding specificity of verotoxins from Gal 1-4Gal to GalNAc 1-3Gal 1-4Gal and vice versa by site-directed mutagenesis of the binding subunit
49. Identification of three amino acid residues in the B subunit of Shiga toxin and Shiga-like toxin type that are essential for holotoxin activity
50. Chromosome of the enterohemorrhagic Escherichia coli O157:H7; comparative analysis with K-12 MG1655 revealed the acquisition of a large amount of foreign DNAs
51. Exploitation of host cells by enteropathogenic Escherichia coli
52. Cloning and sequencing of the genes for Shiga toxin from Shigella dysenteriae type 1
53. Cloning and primary structure of Shigella toxin genes
54. Isolation of Shigella sonnei lysogenic for bacteriophage encoding gene for production of Shiga toxin
55. Enterobacter cloacae producing a shiga-like toxin II-related cytotoxin associated with a case of hemolytic uremic syndrome
56. Shiga-like toxin II-related cytotoxins in Citrobacter freundii strains from humans and beef samples