Electrophysiologic basis by which epinephrine facilitates defibrillation after prolonged episodes of ventricular fibrillation

Annals of Emergency Medicine

Volumn 38, Issue 3, 2001, Pages 201-206

  Suddath, William O ^a   Deychak, Yuri ^a   Varghese, P Jacob ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SYNCHRONIZATION; CONTROLLED STUDY; DEFIBRILLATION; DRUG EFFECT; ELECTRIC ACTIVITY; ELECTROPHYSIOLOGY; HEART MASSAGE; HEART REPOLARIZATION; HEART VENTRICLE FIBRILLATION; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION; SWINE;

EID: 0034838293     PISSN: 01960644     EISSN: None     Source Type: Journal    
DOI: 10.1067/mem.2001.115540     Document Type: Article

References (15)

1. Guidelines for CPR and Emergency Cardiac Care. Emergency Cardiac Care Committee and Sub Committees. American Heart Association. Part III adult advanced cardiac life support
2. Improving survival from sudden cardiac arrest: The 'Chain of Survival' concept: A statement for health professionals from the Advanced Cardiac Life Support Sub Committee and the Emergency Cardiac Care Committee, American Heart Association
3. Mechanisms by which epinephrine augments cerebral and myocardial perfusions during cardiopulmonary resuscitation in dogs
4. Adrenergic effects on ventricular vulnerability
5. Epinephrine reduces ventricular fibrillation threshold and stabilizes fibrillation by reducing cellular refractory period during fibrillation
6. Effect of epinephrine on the efficacy of the internal cardioverter-defibrillator
7. Outcome of out-of-hospital cardiac arrest in New York City: The Pre-Hospital Arrest Survival Evaluation (PHASE) Study
8. Ventricular refractory period extension caused by defibrillation shocks
9. Biphasic wave forms enhance defibrillation success by prolonging refractoriness to refibrillating wave fronts
10. The conditioning forepulse of biphasic defibrillation wave forms enhances refractoriness to fibrillation wave fronts
11. Official recordings in the rabbit heart show that defibrillation strength shocks prolong the duration of depolarization and the refractory period
12. Synchronized repolarization after defibrillation shocks. A possible component of the defibrillation process demonstrated by optical recordings in rabbit heart
13. Mechanism of spontaneous defibrillation in the rabbit heart
14. Amplitude of ventricular fibrillation wave form and outcome after cardiac arrest
15. Epinephrine facilitates fibrillation by shortening action potential duration and refractory period at ventricular tachycardia/fibrillation cycle lengths