Dynein motors of the Chlamydomonas flagellum

International Review of Cytology

Volumn 210, Issue , 2001, Pages 227-268

  DiBella, L M ^a   King, S M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Axoneme; Chlamydomonas; Dynein; Flagellum; Microtubule; Motility

Indexed keywords

ACTIN; CELL ENZYME; CENTRIN; DYNEIN ADENOSINE TRIPHOSPHATASE; LC8 ENZYME; MOLECULAR MOTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AXONEME; BIOCHEMISTRY; CELL MOTILITY; CHLAMYDOMONAS; FLAGELLUM; GENETICS; HYDROLYSIS; MICROTUBULE; MOLECULAR CLONING; MOLECULAR WEIGHT; MOTION; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

CHLAMYDOMONAS;

EID: 0034833751     PISSN: 00747696     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0074-7696(01)10007-0     Document Type: Article

References (196)

1. A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox-regulated, cAMP-mediated induction of tyrosine phosphorylation
2. Dynein arm substructure and the orientation of arm-microtubule attachments
3. The proteasome
4. The "8-kD" cytoplasmic dynein light chain is required for nuclear migration and for dynein heavy chain localization in Aspergillus nidulans
5. Dimerization of the highly conserved light chain shared by dynein and myosin V
6. Light chain 1 from the Chlamydomonas outer dynein arm is a leucine-rich repeat protein associated with the motor domain of the γ heavy chain
7. Calcium control of waveform in isolated flagellar axonemes of Chlamydomonas
8. Drosophila roadblock and Chlamydomonas LC7: A conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis
9. Bending patterns of Chlamydomonas flagella: IV. Mutants with defects in inner and outer dynein arms indicate differences in dynein arm function
10. Identification and insertional mutagenesis of a new Chlamydomonas reinhardtii gene, ODA14, that encodes the 25-kDa subunit of the outer dynein arm docking complex (ODA-DC)
11. Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons
12. A novel cytoplasmic dynein heavy chain: Expression of DHC1b in mammalian ciliated epithelial cells
13. Light-regulated translation of chloroplast messenger RNAs through redox potential
14. The Tctex1/Tctex2 class of dynein light chains: Dimerization, differential expression and interaction with the LC8 protein family
15. Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster
16. Molecular and genetic characterization of SLC1, a putative Saccharomyces cerevisiae homolog of the metazoan cytoplasmic dynein light chain 1
17. Dynein light chain binding to a 3′-untranslated sequence mediates parathyroid hormone mRNA association with microtubules
18. The light chain composition of chicken brain myosin-Va: Calmodulin, myosin-II essential light chains, and 8-kDa dynein light chain/PIN
19. An axonemal dynein at the Hybrid Sterility 6 locus: Implications for t haplotype-specific male sterility and the evolution of species barriers
20. Components of a "dynein regulatory complex" are located at the junction between the radial spokes and the dynein arms in Chlamydomonas flagella
21. Outer arm dynein from trout spermatozoa. Purification, polypeptide composition, and enzymatic properties
22. An extended microtubule-binding structure within the dynein motor domain
23. Tracking kinesin-driven movements with nanometre-scale precision
24. Phylogeny and expression of axonemal and cytoplasmic dynein genes in sea urchins
25. Multiple nucleotide-binding sites in the sequence of dynein β heavy chain
26. Photosensitized cleavage of dynein heavy chains. Cleavage at the "V1 site" by irradiation at 365 nm in the presence of ATP and vanadate
27. Structural comparison of purified dynein proteins with in situ dynein arms
28. Regulation of flagellar dynein by an axonemal type-1 phosphatase in Chlamydomonas
29. Regulation of flagellar dynein by phosphorylation of a 138-kD inner arm dynein intermediate chain
30. Interaction mapping of a dynein heavy chain. Identification of dimerization and intermediate chain-binding domains
31. The molecular anatomy of dynein
32. Identification of the t complex-encoded cytoplasmic dynein light chain Tctex1 in inner arm I1 supports the involvement of flagellar dyneins in meiotic drive
33. Stimulation of in vitro motility of Chlamydomonas axonemes by inhibition of cAMP-dependent phosphorylation
34. Cellular and viral protein interactions regulating IκBα activity during human retrovirus infection
35. Regulation and products of the Ubx domain of the bithorax complex
36. Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase
37. Paralyzed flagellar mutants of Chlamydomonas reinhardtii defective for axonemal doublet microtubule arms
38. Suppressor mutations in Chlamydomonas reveal a regulatory mechanism for flagellar function
39. Tctex2: A sperm tail surface protein mapping to the t-complex
40. PIN: An associated protein inhibitor of neuronal nitric oxide synthase
41. Structure and molecular weight of the dynein ATPase
42. Translocation and rotation of microtubules caused by multiple species of Chlamydomonas inner-arm dynein
43. Microtubule translocation caused by three subspecies of inner-arm dynein from Chlamydomonas flagella
44. Molecular cloning of Fyn-associated molecules in the mouse central nervous system
45. High-frequency nanometre-scale vibration in 'quiescent' flagellar axonemes
46. Mutations at twelve independent loci result in absence of outer dynein arms in Chlamydomonas reinhardtii
47. Two types of Chlamydomonas flagellar mutants missing different components of inner-arm dynein
48. A genetic approach to the function of inner and outer arm dynein
49. A mutant of Chlamydomonas reinhardtii that lacks the flagellar outer dynein arm but can swim
50. Submicromolar levels of calcium control the balance of beating between the two flagella in demembranated models of Chlamydomonas
51. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex
52. Isolation of two species of Chlamydomonas reinhardtii flagellar mutants, ida5 and ida6, that lack a newly identified heavy chain of the inner dynein arm
53. Chlamydomonas inner-arm dynein mutant, ida5, has a mutation in an actin-encoding gene
54. Highly divergent actin expressed in a Chlamydomonas mutant lacking the conventional actin gene
55. Phosphoregulation of an inner dynein arm complex in Chlamydomonas reinhardtii is altered in phototactic mutant strains
56. The bop2-1 mutation reveals radial asymmetry in the inner dynein arm region of Chlamydomonas reinhardtii
57. AAA domains and organization of the dynein motor unit
58. Cytoplasmic dynein contains a family of differentially expressed light chains
59. r 8,000 light chain
60. The mouse t-complex-encoded protein Tctex-1 is a light chain of brain cytoplasmic dynein
61. Structure of the α and β heavy chains of the outer arm dynein from Chlamydomonas flagella. Nucleotide binding sites
62. 2+-binding light chain within Chlamydomonas outer arm dynein
63. (r) = 8,000 and 11,000 outer arm dynein light chains from Chlamydomonas flagella have cytoplasmic homologues
64. (r) intermediate chain of Chlamydomonas outer arm dynein is a microtubule-binding protein
65. r78,000 intermediate chain of Chlamydomonas outer arm dynein interacts with α-tubulin in situ
66. Structure of the α and β heavy chains of the outer arm dynein from Chlamydomonas flagella. Masses of chains and sites of ultraviolet-induced vanadate-dependent cleavage
67. Structure of the γ heavy chain of the outer arm dynein from Chlamydomonas flagella
68. Localization of an intermediate chain of outer arm dynein by immunoelectron microscopy
69. Multiple sites of phosphorylation within the α heavy chain of Chlamydomonas outer arm dynein
70. Identification of a microtubule-binding domain in a cytoplasmic dynein heavy chain
71. Dynein from Dictyostelium: Primary structure comparisons between a cytoplasmic motor enzyme and flagellar dynein
72. Functional elements within the dynein microtubule-binding domain
73. Dynein light chains of the Roadblock/LC7 group belong to an ancient protein superfamily implicated in NTPase regulation
74. The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex
75. A motility in the eukaryotic flagellum unrelated to flagellar beating
76. Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit
77. Tctex-1: A candidate gene family for a mouse t complex sterility locus
78. Ida4-1, ida4-2, and ida4-3 are intron splicing mutations affecting the locus encoding p28, a light chain of Chlamydomonas axonemal inner dynein arms
79. The light chain p28 associates with a subset of inner dynein arm heavy chains in Chlamydomonas axonemes
80. Cloning and characterization of a gene encoding an actin-related protein in Chlamydomonas
81. Specific cleavage of dynein heavy chains by ultraviolet irradiation in the presence of ATP and vanadate
82. Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein
83. Structure of the PIN/LC8 dimer with a bound peptide
84. Novel transcripts from the Ultrabithorax domain of the bithorax complex
85. The 8 kDa dynein light chain binds to its targets via a conserved "K/R-X-T-Q-T" motif
86. Genetic and biochemical dissection of the eucaryotic flagellum
87. Dynein arm mutants of Chlamydomonas
88. Structure and mass analysis of 14S dynein obtained from Tetrahymena cilia
89. Arrangement of inner dynein arms in wild-type and mutant flagella of Chlamydomonas
90. Extrusion of rotating microtubules on the dynein-track from a microtubule-dynein γ-complex
91. Sequence analysis of the Chlamydomonas α and β dynein heavy chain genes
92. Identification of oda6 as a Chlamydomonas dynein mutant by rescue with the wild-type gene
93. Reversion analysis of dynein intermediate chain function
94. A motile Chlamydomonas flagellar mutant that lacks outer dynein arms
95. A circular dichroic study of helical structure in flagellar dynein
96. Phase partition analysis of nucleotide binding to axonemal dynein
97. Probing the nucleotide binding sites of axonemal dynein with the fluorescent nucleotide analogue 2′(3′)-O-(-N-Methylanthraniloyl)adenosine 5′-triphosphate
98. A map of photolytic and tryptic cleavage sites on the β heavy chain of dynein ATPase from sea urchin sperm flagella
99. Structure of Tctex-1 and its interaction with cytoplasmic dynein intermediate chain
100. The motile β/IC1 subunit of sea urchin sperm outer arm dynein does not form a rigor bond
101. The α subunit of sea urchin sperm outer arm dynein mediates structural and rigor binding to microtubules
102. Identification of a dynein molecular motor component in Torpedo electroplax: Binding and phosphorylation of Tctex-1 by Fyn
103. The Chlamydomonas Dhc1 gene encodes a dynein heavy chain subunit required for assembly of the I1 inner arm complex
104. Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport
105. The ancient regulatory protein family of WD-repeat proteins
106. AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
107. Four ATP-binding sites in the midregion of the β heavy chain of dynein
108. Is outer arm dynein intermediate chain 1 multifunctional?
109. Recovery of flagellar inner-arm dynein and the fertilization tubule in Chlamydomonas ida5 mutant by transformation with actin genes
110. S.pombe gene sds22+ essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1
111. Models for male infertility: The t haplotypes
112. ATP analogs substituted on the 2-position as substrates for dynein ATPase activity
113. Ability of paralyzed flagellar mutants of Chlamydomonas to move
114. Identification of a germ-cell-specific transcriptional repressor in the promoter of Tctex-1
115. Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function
116. Two functional thioredoxins containing redox-sensitive vicinal dithiols from the Chlamydomonas outer dynein arm
117. A Chlamydomonas homologue of the putative murine t complex distorter Tctex-2 is an outer arm dynein light chain
118. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene Tg737, are required for assembly of cilia and flagella
119. The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly
120. LC2, the Chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly
121. A dynein light chain is essential for the retrograde particle movement of intralagellar transport (IFT)
122. Forward and reverse genetic analysis of microtubule motors in Chlamydomonas
123. Insights into the structural organization of the I1 inner arm dynein from a domain analysis of the 1β dynein heavy chain
124. The Chlamydomonas IDA7 locus encodes a 140-kDa dynein intermediate chain required to assemble the I1 inner arm complex
125. Purification and polypeptide composition of dynein ATPases from Chlamydomonas flagella
126. Subfractionation of Chlamydomonas 18 S dynein into two unique subunits containing ATPase activity
127. Mutations in the 8 kDa dynein light chain gene disrupt sensory axon projections in the Drosophila imaginal CNS
128. Axonemal adenosine triphosphatases from flagella of Chlamydomonas reinhardtii. Purification of two dyneins
129. Inner arm dyneins from flagella of Chlamydomonas reinhardtii
130. Mutations in the "dynein regulatory complex" alter the ATP-insensitive binding sites for inner arm dyneins in Chlamydomonas axonemes
131. The inner dynein arms 12 interact with a "dynein regulatory complex" in Chlamydomonas flagella
132. The proximal portion of Chlamydomonas flagella contains a distinct set of inner dynein arms
133. Three distinct inner dynein arms in Chlamydomonas flagella: Molecular composition and location in the axoneme
134. Distinct mutants of retrograde intraflagellar transport (IFT) share similar morphological and molecular defects
135. Axonemal dyneins: Assembly, organization, and regulation
136. Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas
137. Mutations in the SUP-PF-1 locus of Chlamydomonas reinhardtii identify a regulatory domain in the β-dynein heavy chain
138. The dynein gene family in Chlamydomonas reinhardtii
139. Extragenic suppressors of paralyzed flagellar mutations in Chlamydomonas reinhardtii identify loci that alter the inner dynein arms
140. The 9 + 2 axoneme anchors multiple inner arm dyneins and a network of kinases and phosphatases that control motility
141. Crystal structure of the spliceosomal U2B″-U2A′ protein complex bound to a fragment of U2 small nuclear RNA
142. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
143. Interaction of the rabies virus P protein with the LC8 dynein light chain
144. Insights into the mechanism of homologous recombination from the structure of RuvA
145. Intraflagellar transport: The eyes have it
146. Identification of the RII binding site in radial spoke protein 3, a Chlamydomonas axonemal AKAP
147. The suppf-2 mutations of Chlamydomonas alter the activity of the outer dynein arms by modification of the γ-dynein heavy chain
148. Inner-arm dynein c of Chlamydomonas flagella is a single-headed processive motor
149. A Chlamydomonas outer arm dynein mutant missing the α heavy chain
150. Translocation of microtubules caused by the αβ, β and γ outer arm dynein subparticles of Chlamydomonas
151. A Chlamydomonas outer arm dynein mutant with a truncated β heavy chain
152. 2+ modulates the microtubule-binding activity of the βγ and γ heavy chain subparticles of Chlamydomonas outer arm dynein
153. The substructure of isolated and in situ outer dynein arms of sea urchin sperm flagella
154. Structural characterization of a dynein motor domain
155. The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes
156. Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans
157. The peculiar journey of a selfish chromosome
158. Microtubule binding and translocation by inner dynein arm subtype I1
159. Regulation of dynein-driven microtubule sliding by the radial spokes in flagella
160. Crystal structure of a G-protein β/γ dimer at 2.1 Å resolution
161. Smart machines at the replication fork
162. Cloning and characterization of the actin-encoding gene of Chlamydomonas reinhardtii
163. Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries
164. Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice
165. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1
166. Mutational analysis of centrin: An EF-hand protein associated with three distinct contractile fibers in the basal body apparatus of Chlamydomonas
167. Functional reconstitution of Chlamydomonas outer dynein arms from α-β and γ subunits: Requirement of a third factor
168. Three-headed outer arm dynein from Chlamydomonas that can functionally combine with outer-arm-missing axonemes
169. Structure of the dynein-1 outer arm in sea urchin sperm flagella. I. Analysis by separation of subunits
170. Photosensitized cleavage of dynein heavy chains. Cleavage at the V2 site by irradiation at 365 nm in the presence of oligovanadate
171. Solution structure of a protein inhibitor of neuronal nitric oxide synthase
172. Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles
173. AAA proteins. Lords of the ring
174. Rotation and translocation of microtubules in vitro induced by dyneins from Tetrahymena cilia
175. Single cytoplasmic dynein molecule movements: Characterization and comparison with kinesin
176. Cloning, expression and mapping of TCTEL1, a putative human homolog of murine Tctel, to 6q
177. High level expression in Escherichia coli and characterization of the EF-hand calcium-binding protein caltractin
178. Processing of recombination intermediates by the Ruv ABC proteins
179. (r) intermediate chain of Chlamydomonas outer arm dynein is a WD-repeat protein required for arm assembly
180. Molecular analysis of the γ heavy chain of Chlamydomonas flagellar outer-arm dynein
181. Dynein heavy chains have at least two functional ATP-binding sites
182. Chlamydomonas phototaxis
183. Fine structure and molecular weight of the outer arm dyneins of Chlamydomonas
184. The intermediate chain/light chain complex: An important structural entity of outer arm dynein
185. Dynein arm conformation and mechano-chemical transduction in the eukaryotic flagellum
186. 13C resonance assignments for the 22 kDa LC1 light chain from Chlamydomonas outer arm dynein
187. 13C resonance assignments for the Tctex1 dynein light chain from Chlamydomonas flagella
188. Solution structure of a dynein motor domain associated light chain
189. ADP-dependent microtubule translocation by flagellar inner-arm dyneins
190. Nanometer scale vibration in mutant axonemes of Chlamydomonas
191. Structural interaction of calmodulin, dynein light chain LC8 and radial spoke protein 2 in the flagellar radial spoke
192. r140,000 intermediate chain of Chlamydomonas flagellar inner arm dynein is a WD-repeat protein implicated in dynein arm anchoring
193. Casein kinase I is anchored on axonemal doublet microtubules and regulates flagellar dynein phosphorylation and activity
194. Structure and subunit composition of the RuvAB-Holliday junction complex
195. Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP