Proteomics in early detection of cancer

Clinical Chemistry

Volumn 47, Issue 10, 2001, Pages 1901-1911

  Srinivas, P R ^a   Srivastava, S ^a   Hanash, S ^a   Wright G L , Jr ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BIOLOGICAL MARKER; PROTEOME;

CANCER CONTROL; CANCER DIAGNOSIS; CANCER PREVENTION; CONFERENCE PAPER; DESORPTION; DISEASE MARKER; EARLY DIAGNOSIS; HUMAN; IONIZATION; MALIGNANT TRANSFORMATION; MASS SPECTROMETRY; RESEARCH; RISK ASSESSMENT; TWO DIMENSIONAL ELECTROPHORESIS;

EID: 0034828488     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/47.10.1901     Document Type: Conference Paper

References (83)

1. Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium
2. Proteomics: New perspectives, new biomedical opportunities
3. Proteomics: Applications in basic and applied biology
4. The current state of two-dimensional electrophoresis with immobilized pH gradients
5. Biomedical applications of two-dimensional electrophoresis using immobilized pH gradients: Current status
6. '98 Escherichia coli SWISS-2DPAGE database update
7. Proteomics: A new approach to the study of disease
8. SYPRO ruby and SYPRO red protein gel stains
9. Identification of gel-separated tumor marker proteins by mass spectrometry
10. High-throughput profiling of the mitochondrial proteome using affinity fractionation and automation
11. Proteome profiling of bladder squamous cell carcinomas: Identification of markers that define their degree of differentiation
12. Psoriasin (S100A7): A putative urinary marker for the follow up patients with bladder squamous cell carcinomas
13. Proteomics in human disease: Cancer, heart and infectious diseases
14. Renal cell carcinoma and normal kidney protein expression
15. Tumor progression- and metastasis-associated proteins identified using a model of locally recurrent rat mammary adenocarcinomas
16. A database of protein expression in lung cancer
17. Expression of tropomyosin isoforms in benign and malignant human breast lesions
18. Assessment of homogeneity in polypeptide expression in breast carcinomas shows widely variable expression in highly malignant tumors
19. Analysis of polypeptide expression in benign and malignant human breast lesions: Down-regulation of cytokeratins
20. Characterization of gene expression in clinical lung cancer materials by two-dimensional polyacrylamide gel electrophoresis
21. Relationship between TA01 and TA02 polypeptides associated with lung adenocarcinoma and histocytological features
22. Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas
23. Phenotype analysis of ovarian carcinoma: Polypeptide expression in benign, borderline and malignant tumors
24. Cancer proteomics: From identification of novel markers to creation of artificial learning models for tumor classification
25. Proliferation-related expression of p19/nm23 nucleoside diphosphate kinase
26. Electrospray ionization for mass spectrometry of large biomolecules
27. Laser desorption ionization of proteins with molecular masses exceeding 10 000 daltons
28. Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers
29. Functional genomics by mass spectrometry
30. Rapidly switchable matrix-assisted laser desorption/ionization and electrospray quadrupole-time-of-flight mass spectrometry for protein identification
31. MALDI quadrupole time-of-flight mass spectrometry: A powerful tool for proteomic research
32. Recent advancements in surface-enhanced laser desorption/ionization-time of flight-mass spectrometry
33. Modified expression of plasma glutathione peroxidase and manganese superoxide dismutase in human renal cell carcinoma
34. Proteomic analysis reveals that 14-3-3σ is down-regulated in human breast cancer cells
35. High frequency of hypermethylation at the 14-3-3σ locus leads to gene silencing in breast cancer
36. Imaging mass spectrometry: A new technology for the analysis of protein expression in mammalian tissues
37. Direct profiling of proteins in biological tissue sections by MALDI mass spectrometry
38. ProteinChip surface enhanced laser desorption/ionization (SELDI) mass spectrometry: A novel protein biochip technology for detection of prostate cancer biomarkers in complex protein mixtures
39. Identifying the signature proteins of prostate cancer in seminal plasma by SELDI affinity mass spectrometry
40. Protein protiling of seminal plasma and serum using Ciphergen's SELDI ProteinChip technology for early detection of prostate cancer
41. Discovery of prostate cancer biomarkers from laser capture microdissected (LCM) cells using innovative proteinchip SELDI mass spectroscopy
42. Rapid protein display profiling of cancer progression directly from human tissue using a protein biochip
43. Surface enhanced laser desorption/ionization analysis of human lung cancer specimens
44. Protein profiling of epithelial ovarian tumors by surface enhanced laser desorption/ionization (SELDI) analysis
45. Development of a novel proteomic approach for the detection of transitional cell carcinoma of the bladder in urine
46. A learning algorithm diagnosis prostate and ovarian cancer from human serum based on multiparametric proteomic patterns
47. Detection of serum breast cancer markers by mass spectrometry
48. A novel biochip SELDI mass spectrometry immunoassay for quantitation of prostate specific membrane antigen (PSMA) in body fluids
49. Generation of a baculovirus recombinant prostate-speacific membrane antigen and its use in the development of a novel lprotein biochip quantitative immunoassay
50. Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid
51. Antibody arrays for high throughput screening of antibody-antigen interactions
52. Protein microchips: Use for immunoassay and enzymatic reactions
53. Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions
54. Protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
55. Protein and antibody arrays and their medical applications
56. Tissue microarrays for high-throughput molecular profiling of tumor specimens
57. Validation of tissue microarrays for immunohistochemical profiling of cancer specimens using the example of human firoblastic tumors
58. Validation of tissue microarray technology in breast cancer
59. Neuroendocrine expression in metastatic prostate cancer: Evaluation of high throughput tissue microarrays to detect heterogeneous protein expression
60. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
61. Identifying proteins in genome databases using mass spectrometry
62. A distributed system for two-dimensional gel analysis
63. Mining protein data from two-dimensional gels: Tools for systematic post-planned analyses
64. Loss of adipocyte-type fatty acid binding protein and other protein biomarkers is associated with progression of human bladder transitional cell carcinomas
65. A two-dimensional gel database of human colon carcinoma proteins
66. Sharing of world wide web spread knowledge using hypermedia facilities and fast communication protocols (Mosaic and world web): The example of ExPaSy
67. The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1998
68. Lung tumor cells: A multivariate approach to cell classification using two-dimensional protein pattern
69. Computerized classification of two-dimensional gel electrograms by correspondence analysis and ascendant hierarchical clustering
70. Application of wavelet transformations to experimental spectra: Smoothing, denoising, and data set compression
71. Classification procedures using principal component analysis and stepwise discriminant function
72. Improving protein identification from peptide mass fingerprinting through a parameterized multi-level scoring algorithm and an optimized peak detection
73. Cancer proteomics: From biomarker discovery to signal pathway
74. Proteomics meet cell biology. The establishment of subcellular proteomes
75. Current challenges and future applications for protein maps and posttranslational vector maps in proteome projects
76. Laser capture microdissection
77. Laser capture microdissection: Molecular analysis of tissue
78. Ablation of polymers and biological tissue by ultraviolet lasers
79. Characterization of intracellular prostate-specific antigen from laser capture microdissected benign and malignant prostatic epithelium
80. Proteomic analysis of laser captured microdissected human prostate cancer and in vitro cell lines
81. The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomics analysis: Preliminary findings