Simultaneous administration of a cocktail of markers to measure renal drug elimination pathways: Absence of a pharmacokinetic interaction between fluconazole and sinistrin, p-aminohippuric acid and pindolol

British Journal of Clinical Pharmacology

Volumn 51, Issue 6, 2001, Pages 547-555

  Gross, A S ^a   McLachlan, A J ^a   Minns, I ^b   Beal, J B ^c   Tett, S E ^c,d  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d PRINCE OF WALES HOSPITAL   (Australia)

Author keywords

Creatinine clearance; Fluconazole; Pindolol; Renal drug elimination; Tubular reabsorption; Tubular secretion

Indexed keywords

4 AMINOHIPPURIC ACID; FLUCONAZOLE; FRUCTAN; PINDOLOL;

ADULT; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG URINE LEVEL; GLOMERULUS FILTRATION; HUMAN; HUMAN EXPERIMENT; KIDNEY CLEARANCE; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE EXCRETION; MALE; MEASUREMENT; NORMAL HUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; STATISTICS; ULTRAFILTRATION; URINARY EXCRETION; VALIDATION PROCESS;

ADMINISTRATION, ORAL; ADULT; ANTIFUNGAL AGENTS; BIOLOGICAL MARKERS; CREATININE; DRUG COMBINATIONS; DRUG MONITORING; FLUCONAZOLE; GLOMERULAR FILTRATION RATE; HALF-LIFE; HUMANS; INFUSIONS, INTRAVENOUS; KIDNEY; KIDNEY TUBULES; MALE; OLIGOSACCHARIDES; PINDOLOL; RENAL PLASMA FLOW; TIME FACTORS;

EID: 0034825501     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2001.01390.x     Document Type: Article

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