Signal integration in lipopolysaccharide (LPS)-stimulated murine macrophages

Journal of Endotoxin Research

Volumn 7, Issue 3, 2001, Pages 237-241

  Vogel, Stefanie ^a   Perera, Pin Yu ^a   Hirschfeld, Matthew J ^b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD11B ANTIGEN; CD14 ANTIGEN; CD18 ANTIGEN; CYCLOOXYGENASE 2; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PACLITAXEL; PROTEIN P35; PROTEIN P40; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE INDUCTION; GENETIC SELECTION; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PORPHYROMONAS GINGIVALIS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD14; ANTIGENS, CD18; DROSOPHILA PROTEINS; ESCHERICHIA COLI; GENE EXPRESSION; LIPOPOLYSACCHARIDES; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0034824735     PISSN: 09680519     EISSN: None     Source Type: Journal    
DOI: 10.1179/096805101101532747     Document Type: Article

References (16)

1. The molecular pathogenesis of endotoxic shock and organ failure
2. Dissection of LPS-induced signaling pathways in murine macrophages using LPS analogs, LPS mimetics, and agents unrelated to LPS
3. d) macrophages
4. Lipopolysaccharide and monophosphoryl lipid A differentially regulate interleukin-12, gamma interferon, and interleukin-10 mRNA production in murine macrophages
5. CD11b/CD18 acts in concert with CD14 and toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression
6. Signaling by TLR2 vs. TLR4 agonists results in differential gene expression in murine macrophages
7. Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235
8. Elimination of trace endotoxin protein from rough chemotype LPS
9. Repurification of LPS eliminates signaling through both human and murine Toll-like receptor 2
10. Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
11. Resistance to endotoxin shock and reduced dissemination of Gram-bacteria in CD14 negative-deficient mice
12. A novel role for the beta 2 integrin CD11b/CD18 in neutrophil apoptosis: A homeostatic mechanism in inflammation
13. Use of a photoactivatable Taxol analog to identify unique cellular targets: Identification of murine CD18 as a major Taxol-binding protein and a role for Mac-1 in Taxol-induced gene expression
14. CD14-dependent and CD14-independent signaling pathways in murine macrophages from normal and CD14 'knockout' mice stimulated with LPS or Taxol
15. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides
16. The biology of Toll-like receptors