Antioxidant effects of D002 on the in vitro susceptibility of whole plasma in healthy volunteers

Archives of Medical Research

Volumn 32, Issue 5, 2001, Pages 436-441

  Menendez R ^a   Mas R ^a   Amor, A M ^a   Perez Y ^a   Gonzalez R M ^a   Fernandez J ^a   Molina, V ^a   Jimenez S ^a  

^a NATL CENTER FOR SCIENTIFIC RESEARCH   (Cuba)

Author keywords

D002; Healthy volunteers; Lipid peroxidation; Triacontanol

Indexed keywords

ALCOHOL DERIVATIVE; ALKADIENE; ANTIOXIDANT; COPPER; DOTRIACONTANOL; GLUTATHIONE PEROXIDASE; HEXACOSANOL; OCTACOSANOL; PROPOLIS; SUPEROXIDE DISMUTASE; TETRACOSANOL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACONTANOL; UNCLASSIFIED DRUG;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; FOLLOW UP; HUMAN; LIPID PEROXIDATION; MALE; NORMAL HUMAN; OPTICAL DENSITY; OXIDATION; RANDOMIZED CONTROLLED TRIAL; VOLUNTEER;

ADMINISTRATION, ORAL; ADULT; ANTIOXIDANTS; BLOOD PROTEINS; COPPER; DOUBLE-BLIND METHOD; FATTY ALCOHOLS; FEMALE; GLUTATHIONE PEROXIDASE; HUMANS; LIPID PEROXIDATION; MALE; MIDDLE AGED; OXIDATION-REDUCTION; REFERENCE VALUES; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0034824625     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0188-4409(01)00315-0     Document Type: Article

References (53)

1. Anti-ulcer activity of higher primary alcohols of beeswax
2. Possible cytoprotective mechanism in rats of D002, an anti-ulcerogenic product isolated from beeswax
3. Role of oxygen radicals in ethanol-induced damage to cultured gastric mucosal cells
4. Free radical and lipid peroxidation in ethanol and aspirin induced gastric mucosal injury
5. Removing oxygen-derived free radicals stimulates healing of ethanol-induced erosive gastritis in the rat
6. Pentoxifillyne-associated reduction of endomethacin-induced rat gastric mucosal injury supported by decreased lipid peroxidation
7. Anti-inflammatory activity of D002: An active product isolated from beeswax
8. Free radicals as mediators of tissue injury and disease
9. Inhibition of rat microsomal lipid peroxidation by the oral administration of D002
10. Triacontanol inhibits both enzymatic and nonenzymatic lipid peroxidation
11. Copper-induced lipid oxidation in unfractionated plasma: The lag preceding oxidation as a measure of oxidation-resistance
12. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
13. The reaction between thiobarbituric acid and the oxidation products of certain lipids
14. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury
15. Superoxide dismutase: An enzymatic function for erythrocuprein (hemocuprein)
16. Superoxide dismutases: A history
17. Glutathione peroxidase brought into focus
18. Towards the physiological function of uric acid
19. Ascorbate is an outstanding antioxidant in human blood plasma
20. The relative contribution of vitamin E, urate, ascorbic acid and proteins to the total peroxyl radical trapping antioxidant activity of human blood plasma
21. Toxicología aguda del D002 en ratas Sprague Dawley
22. Preclinical toxicology in rats of D002, a natural drug with antiulcer activity
23. Oral toxicological studies of D002 in mice
24. Toxicity of D002 a mixture of aliphatic primary alcohols in beagle dogs: One year study
25. Flavonoid antioxidants: Rate constant for reactions with oxygen radicals
26. Phenolic antioxidants
27. Total phenolic and antioxidant activity of commercial wines, teas and fruit juices
28. Antioxidant effects of estradiol and 2-hydroxyestradiol on iron-induced lipid peroxidation of rat liver microsomes
29. Paracetamol inhibits copper ion, azo compound-initiated and mononuclear cell-mediated oxidative modification of LDL
30. Inhibitory effect of tea flavonoids on the ability of cells to oxidize low density lipoprotein
31. Inhibition of oxidative modification of LDL by nitecapone
32. Biodistribution and metabolism of orally administered octacosanol in rats
33. Metabolism of octacosanol in liver and muscle of rats
34. Fatty alcohol metabolism in cultured fibroblasts. Evidence for a fatty alcohol cycle
35. Sjögre-Laarsson syndrome. Impaired fatty alcohol oxidation in cultured fibroblasts due to deficient fatty alcohol:Nicotidamide adenine nucleotide oxidoreductase activity
36. Some properties of the fatty alcohol system and reconstitution of microsomal oxidation activity in intestinal mucosa
37. Very long chain fatty acid β-oxidation by rat liver mitochondria and peroxisomes
38. A comparative study of stearic acid and lignocerid acid oxidation by human skin fibroblasts
39. Studies of peroxisomal oxidation of palmitate and lignocerate in rat liver
40. Free radicals, antioxidants and aging
41. Role of free radicals in aging and disease
42. Oxidative damage in neurodegenerative disease
43. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
44. Role of oxygen free radicals in carcinogenesis and brain ischemia
45. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases
46. Plasma retinol, β-carotene and vitamin E levels in relation to the future risk of breast cancer
47. An overview of the relationship between oxidative stress and chemical carcinogenesis
48. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology
49. Vitamin E consumption and the risk of coronary heart disease in men
50. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids
51. The role of lipid peroxidation and antioxidants in oxidative modification of LDL
52. Enhanced in vitro oxidation of plasma lipoprotein derived from hypercholesterolemic patients