Oligonucleotide-polymer nanoparticle conjugates: Diagnostic applications

S.T.P. Pharma Sciences

Volumn 11, Issue 4, 2001, Pages 251-263

  Charles, M H ^a   Charreyre, M T ^a   Delair, T ^a   Elaissari A ^a   Pichot, C ^a  

^a UNIVERSITÉ DE LYON   (France)

Author keywords

Adsorption; Conformation; Covalent grafting; Desorption; Diagnostics; Nanoparticle; Oligonucleotide; Polymer

Indexed keywords

LATEX; NANOPARTICLE; OLIGODEOXYRIBONUCLEOTIDE; OLIGONUCLEOTIDE; PHOSPHATE; POLYMER; SINGLE STRANDED DNA;

AMINO TERMINAL SEQUENCE; CONJUGATION; COVALENT BOND; DIAGNOSTIC TEST; ENERGY TRANSFER; FLUORESCENCE; HYDROPHILICITY; HYDROPHOBICITY; IONIC STRENGTH; PH; PROTEIN CONFORMATION; REVIEW; SALINITY; SURFACE CHARGE;

EID: 0034823127     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (45)

1. Advances in nucleic acid-bases detection methods
2. Syntheses of poly[N-(2,2 dimethoxyethyl)-N-methyl acrylamide for the immobilization of oligonucleotides
3. Characterization of the grafting reaction between oligodeoxyribonucleotides and N-vinyl pyrrolidone/N-acryloxy succinimide copolymers by size exclusion chromatography and free solution capillary electrophoresis
4. Syntheses and characterization of conjugates of nucleic acid probes and aminoglucose based polymers
5. Reactive polymer in diagnostics: Syntheses and characterization of nucleic acid probes and (maleic anhydride-co-methyl vinyl ether) polymers
6. Synthesis and characterization of nucleic acid -(co)polymer conjugates: Application to diagnostics
7. Conformation of DNA block copolymer molecules adsorbed on latex particles as revealed by hydroxyl radical foot-printing
8. Coagulation and stabilization of colloidal particles by adsorbed DNA block copolymers: The role of polymer conformation
9. Preparation of magnetic oligo(dt) particles
10. A versatile solid support system for oligodeoxynucleotide probe-based hybridisation assay
11. Preparation and characterization of cationic polystyrene latex particles of different aminated surface charges
12. Preparation and characterization of cationic poly(n-isopropylacrylamide) copolymer latexes
13. Preparation of conjugates between oligonucleotides and N-vinyl pyrrolidone/N-acryloxysucciminide copolymers and applications in nucleic acid assays to improve sensitivity
14. Protein adsorption and materials biocompatibility
15. Nucleic acid detection with surface plasmon resonance using cationic latex
16. Adsorption of deoxyribonucleic acid and poly(cytidylic acid), poly(inosinic acid) onto polystyrene latex
17. HÉlÈnec. - Polyalkylcyanoacrylate nanoparticles as polymeric carriers for antisense oligonucleotides
18. Adsorption of oligonucleotides onto negatively and positively latex particles
19. Adsorption and desorption studies of polyadenilic acid onto positively charged latex particles
20. Adsorption of single stranded DNA fragments onto cationic aminated latex particles
21. The effect of Triton X-405 on the adsorption and desorption of single-stranded DNA fragments onto positively charged particles
22. Effect of charge nature on the adsorption of single-stranded DNA fragments onto latex particles
23. Amino-containing cationic latex-oligodeoxyribo-nucleotide conjugates: Application to diagnostic test sensitivity enhancement
24. Electrokinetic properties and colloidal stability cationic amino-containing N-isopropylacrylamide styrene copolymer particles bearing different shell structures
25. Dynamic behaviour of flexible polymers at a solid/liquid interface
26. Thermodynamic and kinetic factors in adsorption of polymers on a plane lattice
27. Kinetics of exchange processes in the adsorption of proteins on solid surfaces
28. Functional nanospheres by emulsion polymerisation
29. Oligodeoxyribonucleotide activation with 2,4 phenylene diisothiocyanate and their covalent grafting onto amine-functionalised latex microspheres
30. Covalent grafting of polythymidilic acid onto amine containing polystyrene latex particles
31. Analysis of fluorescence energy transfer in duplex and branched DNA molecules
32. The estimation of distances between specific backbone-labelled sites in DNA using fluorescence resonance energy transfer
33. Fluorescence energy transfer between two triple helix-forming oligonucleotides bound to duplex DNA
34. Fluorescence energy transfer as a probe for nucleic acid structures and sequences
35. Detection of nucleic acid hybridisation by nonradiative fluorescence resonance energy transfer
36. Sensitive fluorescence-based thermodynamic and kinetic measurements of DNA hybridisation in solution
37. Kinetic studies by fluorescence resonance energy transfer employing a double-labelled oligonucleotide: Hybridisation to the oligonucleotide complement and to single-stranded DNA
38. Intracellular oligonucleotide hybridisation detected by fluorescence resonance energy transfer (FRET)
39. Conformational distribution of a four-way DNA junction revealed by time-resolved fluorescence resonance energy transfer
40. Fluorescence energy transfer from fluorescein to tetramethylrhodamine covalently bound to the surface of polystyrene latex particles
41. Synthesis and characterization of cationic amino functionalised polystyrene latexes
42. Fluorescence energy transfer study of the conformation of oligonucleotides covalently bound to polystyrene latex particles
43. Structure of adsorbed and grafted single-stranded DNA fragments on aminated latex particles: A small-angle neutron scattering study