Improved safety with equivalent asthma control in adults with chronic severe asthma on high-dose fluticasone propionate

Respirology

Volumn 6, Issue 3, 2001, Pages 237-246

  Berend, Norbert ^a   Kellett, Bruce ^b   Kent, Neil ^c   Sly, Peter D ^d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Department of Statistical Melbourne ^*  (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Bone metabolism; Hypothalamic pituitary adrenal axis function; Inhaled steroids

Indexed keywords

BECLOMETASONE DIPROPIONATE; BUDESONIDE; CREATININE; DEOXYPYRIDINOLINE; FLUTICASONE PROPIONATE; HYDROCORTISONE; OSTEOCALCIN; PYRIDINOLINE;

ADULT; ARTICLE; ASTHMA; BLOOD LEVEL; BONE TURNOVER; CAPILLARY RESISTANCE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEVICE; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; HOARSENESS; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; TREATMENT OUTCOME; URINE LEVEL;

ADULT; ANDROSTADIENES; ASTHMA; BECLOMETHASONE; BIOLOGICAL MARKERS; BUDESONIDE; CHRONIC DISEASE; CONTUSIONS; CREATININE; FEMALE; GLUCOCORTICOIDS; HOARSENESS; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; OSTEOCALCIN; QUALITY OF LIFE;

EID: 0034822792     PISSN: 13237799     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1843.2001.00329.x     Document Type: Article

References (33)

1. Corticosteroids: A review with emphasis on complications of prolonged systemic therapy
2. Glucocorticoid-induced osteoporosis: Pathogenesis and management
3. Inhaled corticosteroids: Benefits and risks
4. Systemic effects of inhaled corticosteroids in asthma: A comparative risk-profile assessment of fluticasone propionate and budesonide
5. Issues in the use of inhaled corticosteroids
6. Bone physiology and the osteoporotic process
7. Biochemical markers of bone turnover for the assessment of bone metabolism
8. Development of new glucocorticosteroids with a very high ratio between topical and systemic activities
9. A comparison of beclomethasone dipropionate and budesonide in the treatment of asthma
10. High dose fluticasone propionate, 1 mg daily, versus fluticasone propionate 2 mg daily, or, budesonide 1.6 mg daily, in patients with chronic severe asthma
11. Comparison of fluticasone propionate with beclomethasone dipropionate in moderate to severe asthma treated for one year
12. Clinical trials of high-dose fluticasone propionate
13. Reversibility of airflow obstruction: FEV1 vs peak flow
14. Comparison of biochemical markers of bone turnover in Paget disease treated with pamidronate and a proposed model for the relationships between measurements of the different forms of pyridinoline cross-links
15. Fluticasone propionate - An update on preclinical and clinical experience
16. A comparison of the efficacy and safety of inhaled corticosteroids in asthma
17. Relative safety and efficacy of inhaled corticosteroids
18. Fluticasone propionate (FP) in asthma: A meta-analysis of efficacy and systemic activity at clinical recommended doses compared with budesonide (BUD) and beclomethasone dipropionate (BDP)
19. Characterization of a γ-carboxyglutamic acid-containing protein from bone
20. The effects of high-dose glucocorticoid administration on serum bone gamma carboxyglutamic acid-containing protein, serum alkaline phosphatase, and vitamin D metabolites in normal subjects
21. Evaluation of urinary hydroxypyridinium crosslink measurements as resorption markers in metabolic bone diseases
22. Beclomethasone inhalation decreases serum osteocalcin concentrations
23. Bone turnover during high dose inhaled corticosteroid treatment
24. Bone turnover during short course prednisolone treatment in patients with chronic obstructive airways disease
25. Assessment of systemic effects of inhaled glucocorticosteroids: Comparison of the effects of inhaled budesonide and oral prednisolone on adrenal function and markers of bone turnover
26. Effects of dose and dosing schedule of inhaled budesonide on bone turnover
27. Effects of long-term use of high-dose inhaled steroids on bone density and calcium metabolism
28. Effects of short term and long term treatment with inhaled corticosteroids on bone metabolism in patients with airways obstruction
29. Fluticasone propionate does not influence bone metabolism in contrast to beclomethasone dipropionate
30. Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma
31. Cross sectional investigation of the effects of inhaled corticosteroids on bone density and bone metabolism in patients with asthma
32. Skin bruising in asthmatic subjects treated with high doses of inhaled steroids: Frequency and association with adrenal function