Ablation of pituitary pro-opiomelanocortin (POMC) cells produces alterations in hypothalamic POMC mRNA levels and midbrain μ opioid receptor binding in a conditional transgenic mouse model

Journal of Neuroendocrinology

Volumn 13, Issue 9, 2001, Pages 808-817

  Zhou, Y ^a   Unterwald, E M ^a,b   Ho, A ^a   LaForge, K S ^a   Yuferov, V P ^a   Kreuter, J ^a   Sirianni, M J ^c   Allen, R G ^c   Kreek, M J ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Conditional and targeted ablation; CRH; POMC; Quantitative autoradiography; Quantitative solution hybridization; Receptor

Indexed keywords

BETA ENDORPHIN; CORTICOSTERONE; CORTICOTROPIN; DELTA OPIATE RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GANCICLOVIR; GLUCOCORTICOID; KAPPA OPIATE RECEPTOR; MESSENGER RNA; MU OPIATE RECEPTOR; OPIATE; PROOPIOMELANOCORTIN; RIBONUCLEASE; SODIUM CHLORIDE; THYMIDINE KINASE; TRITIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; AUTORADIOGRAPHY; BRAIN REGION; CELL LOSS; CENTRAL GRAY MATTER; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; FUSION GENE; GENE OVEREXPRESSION; GRAY MATTER; HERPES SIMPLEX VIRUS 1; HYBRIDIZATION; HYPOPHYSIS CELL; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOREACTIVITY; INNERVATION; MALE; MEDIAN RAPHE NUCLEUS; MESENCEPHALON; MOUSE; NEGATIVE FEEDBACK; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; STRESS; SUPERIOR COLLICULUS; TRANSGENIC MOUSE;

AMYGDALA; ANIMALS; BRAIN; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; FRONTAL LOBE; HYPOTHALAMUS; MALE; MESENCEPHALON; MICE; MICE, TRANSGENIC; PITUITARY GLAND; PRO-OPIOMELANOCORTIN; PROTEIN-TYROSINE KINASES; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, OPIOID, MU; RNA, MESSENGER; TISSUE DISTRIBUTION;

EID: 0034821536     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.2001.00702.x     Document Type: Article

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