Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes

Biochemical and Biophysical Research Communications

Volumn 285, Issue 3, 2001, Pages 649-655

  Biermanns, Martina ^a   Gärtner, Jutta ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

ATP binding cassette transporter protein; Green fluorescent protein; Peroxin; Peroxisomal membrane protein; Peroxisome; PEX19; PMP70; Targeting

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; AMINO ACID; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; PEROXIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CERCOPITHECIDAE; CONTROLLED STUDY; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; NONHUMAN; PEROXISOME; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION;

EID: 0034817401     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5220     Document Type: Article

References (25)

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8. The sorting sequence of the peroxisomal integral membrane protein PMP47 is contained within a short hydrophilic loop
9. Discrete targeting signals direct Pmp47 to oleate-induced peroxisomes in Saccharomyces cerevisiae
10. Identification and characterization of human PMP34, a protein closely related to the peroxisomal integrale membrane protein PMP47 of Candida boidinii
11. Identification and characterization of the human peroxin PEX3
12. Targeting of the 22 kDa integrale peroxisomal membrane protein
13. Topogenesis of peroxisomal membrane protein requires a short, positively charged interventing-loop sequence and flanking hydrophobic segments
14. PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmatic, and is required for peroxisome membrane synthesis
15. Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interacts with the peroxisomal assembly protein PEX19p
16. Identification of a fourth half ABC transporter in the human peroxisomal membrane
17. The 70 kD peroxisomal membrane protein: An ATP-binding cassette transporter protein involved in the peroxisome biogenesis
18. Cloning and characterization of the gene encoding the human peroxisomal assembly protein PEX3p
19. Newly identified Chinese hamster ovary cell mutants defective in peroxisome assembly represent complementation group A of human peroxisome biogenesis disorders and one novel group in mammals
20. Isolation and characterization of Pas2p, a peroxisomal membrane protein essential for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris
21. A stretch of positively charged amino acids at the N terminus of Hansenula polymorpha Pex3p is involved in incorporation of the protein into the peroxisomal membrane
22. PEX19p, a farnesylated protein essential for peroxisome biogenesis
23. PEX19p interacts wlth Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris
24. PEX17p is required for import of both peroxisome membrane and lumenal proteins and interacts with PEX19p and the peroxisome targeting signal-receptor docking complex in Pichia pastoris
25. The peroxin PEX19p interacts with multiple, integrale membrane proteins at the peroxisomal membrane