Glycerol Dehydrogenase: Structure, Specificity, and Mechanism of a Family III Polyol Dehydrogenase

Structure

Volumn 9, Issue 9, 2001, Pages 789-802

  Ruzheinikov, Sergey N ^a   Burke, Jacky ^a   Sedelnikova, Sveta ^a   Baker, Patrick J ^a   Taylor, Robert ^a   Bullough, Per A ^a   Muir, Nicola M ^b   Gore, Michael G ^b   Rice, David W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Bacillus stearothermophilus; Crystal structure; EC 1.1.1.6; Glycerol dehydrogenase; Glycerol oxidation; Metallo enzyme

Indexed keywords

GLYCEROL DEHYDROGENASE; IDITOL DEHYDROGENASE; IRON; ZINC ION;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; GEOBACILLUS STEAROTHERMOPHILUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BACILLUS STEAROTHERMOPHILUS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; GLYCEROL; HYDROGEN BONDING; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NAD; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUGAR ALCOHOL DEHYDROGENASES; ZINC;

ANIMALIA; GEOBACILLUS STEAROTHERMOPHILUS; NEGIBACTERIA;

EID: 0034813469     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00645-1     Document Type: Article

References (56)

1. Isolation and characterization of glycerol dehydrogenase from Bacillus megaterium
2. Isolation and characterisation of the glycerol dehydrogenase from Bacillus stearothermophilus
3. +-linked glycerol dehydrogenase from Neurospora crassa
4. Glycerol utilization by Schizo-saccharomyces pombe: Dehydration as the initial step
5. Isolation, purification, and some properties of glycerol dehydrogenase from the yeast Candida valida
6. + dependent glycerol dehydrogenase from rabbit skeletal muscle
7. Glycerol dissimilation and its regulation in bacteria
8. Dha system, mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418
9. Cloning and characterization of a gene from Bacillus stearothermophilus var. non-diastaticus encoding a glycerol dehydrogenase
10. Purification, crystallization and quaternary structure analysis of a glycerol dehydrogenase S305C mutant from Bacillus stearothemophilus
11. Analysis of the Esherichia coli genome. 4. DNA-sequence of the region from 89.2 to 92.8 minutes
12. Three-dimensional structure of horse liver alcohol dehydrogenase at 2.4 Å resolution
13. Structure of human β-1,β-1-alcohol dehydrogenase: Catalytic effects of non-active-site substitutions
14. Characteristics of short-chain alcohol dehydrogenases and related enzymes
15. Structural analyses of mutant and wild-type alcohol dehydrogenases from Drosophila melanogaster
16. A mass spectrometry sequence study of the enzyme ribitol dehydrogenase from Klebsiella aerogenes
17. Cloning and expression of rat cDNA-encoding corticosteroid 11-β-dehydrogenase
18. Complete amino acid sequence of human placental 17β-hydroxysteroid dehydrogenase deduced from cDNA
19. The X-ray structure of Brassica napus β-keto acyl carrier protein reductase and its implications for substrate binding and catalysis
20. The 3-dimensional structure of holo 3-alpha,20-β-hydroxysteroid dehydrogenase: A member of a short chain dehydrogenase family
21. An iron-activated alcohol dehydrogenase
22. Homology of Saccharomyces cerevisiae ADH4 to an iron-activated alcohol dehydrogenase from Zymomonas mobilis
23. Constitutive activation of the fucAO operon and silencing of the divergently transcribed fucPIK operon by an IS5 element in Escherichia coli mutants selected for growth on L-1,2-propanediol
24. Cloning, expression, and sequence analysis of the Bacillus methanolicus C1 methanol dehydrogenase gene
25. Structure-function relationships among nicotinamide-adenine dinucleotide dependent oxidoreductases
26. The anatomy and taxonomy of protein structure
27. The interpretation of protein structures: Estimation of static accessibility
28. Abbreviations and symbols for the description of conformations of polynucleotide chains
29. Structure of the active ternary complex of pig heart lactate dehydrogenase with S-lac-NAD at 2.7 Å resolution
30. From crystal statics to chemical dynamics
31. Geometrical preferences for general acid-catalysed hydride transfer: Comparative theoretical study of transition structures for reduction of formaldehyde
32. Dali: A network tool for protein structure comparison
33. Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis
34. Structural consequences of sequence pattern in the fingerprint region of the nucleotide binding fold
35. Rapid and efficient site-specific mutagenesis without phenotypic selection
36. SPIDER - A modular software system for image processing
37. Use of multivariate statistics in analyzing the images of biological macromolecules
38. Correspondence analysis of aligned images of biological particles
39. Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli
40. Finding the structure of objects from projections
41. Iterative methods for the three-dimensional reconstruction of an object from projections
42. Crystallization of glycerol dehydrogenase from Bacillus stearothermophilus
43. Processing of X-ray diffraction data collected in oscillation mode
44. The CCP4 suite: Programs for protein crystallography
45. Maximum likelihood refinement of heavy atom parameters in isomorphous replacement and anomalous scattering
46. Improved method for building protein models in electron density maps and the location of error in these models
47. Crystallography & NMR system: A new software suite for macromolecular structure determination
48. Improved Fourier coefficients for maps using phases from partial structures with errors
49. Protein hydration observed by X-ray diffraction. Solvation properties of penicillopepsin and neuraminidase crystal structures
50. Databases in protein crystallography
51. New parameters for the refinement of nucleic acid containing structures
52. PROCHECK: A program to check the stereochemical quality of protein structures
53. SWISS-MODEL and Swiss-PdbViewer: An environment for comparative protein modelling
54. ALSCRIPT: A tool to format multiple sequence alignments
55. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons