Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 10, 2001, Pages 2838-2844

  Saiman, L ^a   Tabibi, S ^a   Starner, T D ^a   San Gabriel, P ^a   Winokur, P L ^a   Hong Peng Jia, ^a   McCray P B , Jr ^a   Tack, B F ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CEFTAZIDIME; CIPROFLOXACIN; COTRIMOXAZOLE; MEROPENEM; OVISPIRIN 1; OVISPIRIN 2; OVISPIRIN 3; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN CAP18; PROTEIN MCRAMP; PROTEIN RCRAMP; PROTEIN SMAP29; TIMENTIN; TOBRAMYCIN; UNCLASSIFIED DRUG;

ACHROMOBACTER; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL MEMBRANE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; BURKHOLDERIA CEPACIA; CONTROLLED STUDY; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; INHIBITION KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SCANNING ELECTRON MICROSCOPY; STENOTROPHOMONAS MALTOPHILIA; STRAIN DIFFERENCE;

ALCALIGENES; AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; BLOOD PROTEINS; BURKHOLDERIA CEPACIA; CYSTIC FIBROSIS; DRUG RESISTANCE, MULTIPLE; DRUG SYNERGISM; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PEPTIDES; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY, AMINO ACID; SPUTUM; STENOTROPHOMONAS MALTOPHILIA; TIME FACTORS;

EID: 0034812782     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.10.2838-2844.2001     Document Type: Article

References (38)

1. FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis
2. cDNA sequences of three sheep myeloid cathelicidins
3. Microbiology of sputum from patients at cystic fibrosis centers in the United States
4. Use of aerosolized antibiotics in patients with cystic fibrosis
5. Microbial biofilms
6. Bacterial biofilms: A common cause of persistent infections
7. Gender differences in cystic fibrosis: Pseudomonas aeruginosa infection
8. Stenotrophomonas maltophilia in cystic fibrosis: Incidence and prevalence
9. Antimicrobial combinations
10. Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa
11. The changing epidemiology of cystic fibrosis
12. Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse
13. Antiendotoxin activity of cationic peptide antimicrobial agents
14. Comparison of the clinical manifestations of cystic fibrosis in black and white patients
15. Cationic peptides: A new source of antibiotics
16. Peptide antibiotics
17. Chromosomal genetics of Pseudomonas
18. Macromolecular mechanisms of sputum inhibition of tobramycin activity
19. Localization and genomic organization of sheep antimicrobial peptide genes
20. Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization with Pseudomonas aeruginosa
21. Human CAP18: A novel antimicrobial lipopolysaccharide-binding protein
22. Complementary DNA sequence of rabbit CAP18 B a unique lipopolysaccharide binding protein
23. Concurrent assessment of inner and outer membrane permeabilization and bacteriolysis in E. coli by multiple-wavelength spectrophotometry
24. Development of rRNA-based PCR assays for identification of Burkholderia cepacia complex isolates recovered from cystic fibrosis patients
25. Molecular analysis of the sheep cathelin family reveals a novel antimicrobial peptide
26. A novel murine cathelin-like protein expressed in bone marrow
27. Efficacy of aerosolized tobramycin in patients with cystic fibrosis
28. Cystic fibrosis
29. Antibiotic susceptibility of multiply resistant Pseudomonas aeruginosa isolated from cystic fibrosis patients, including transplant candidates
30. Evaluation of reference dilution test methods for antimicrobial susceptibility testing of Pseudomonas aeruginosa isolated from patients with cystic fibrosis
31. SMAP29: A potent antibacterial and antifungal peptide from sheep leukocytes
32. Bactericidal activity of mammalian cathelicidin peptides
33. Molecular epidemiology of Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans in cystic fibrosis center
34. Differentiated structure and function of cultures from human tracheal epithelium
35. Adenovirus-mediated gene transfer to ciliated airway epithelia requires prolonged incubation time
36. Cathelicidins; a novel protein family with a common proregins and a variable C-terminal antimicrobial domain
37. Influence of proline residues on the antibacterial and synergistic activities of alpha-helical peptides