In vitro studies on the immunomodulatory effects of extracts of Osbeckia aspera

Journal of Ethnopharmacology

Volumn 78, Issue 1, 2001, Pages 39-44

  Nicholl, Dawn S ^a   Daniels, Helena M ^a   Ira Thabrew, M ^a   Grayer, Renée J ^b   Simmonds, Monique S J ^b   Hughes, Robin D ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b JODRELL LABORATORY   (United Kingdom)

Author keywords

Chronic hepatitis C; Immunosuppression; Osbeckia aspera; Peripheral blood mononuclear cells

Indexed keywords

ANTIGEN; IONOMYCIN; MITOGENIC AGENT; OSBECKIA ASPERA EXTRACT; PHORBOL 13 ACETATE 12 MYRISTATE; PHYTOHEMAGGLUTININ; PLANT EXTRACT; TUBERCULIN; UNCLASSIFIED DRUG;

ACUTE HEPATITIS; ARTICLE; CELL STIMULATION; CHRONIC HEPATITIS; COMPLEMENT SYSTEM; CONTROLLED STUDY; DRUG EFFECT; HEPATITIS C; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; LIVER PROTECTION; LYMPHOCYTE PROLIFERATION; MONONUCLEAR CELL; OSBECKIA ASPERA; PHAGOCYTOSIS; PLANT; POLYMORPHONUCLEAR CELL; SRI LANKA; VIRUS INFECTION;

ADJUVANTS, IMMUNOLOGIC; ADULT; CELL DIVISION; FEMALE; HEPATITIS C, CHRONIC; HUMANS; IMMUNITY, CELLULAR; LYMPHOCYTES; MALE; MIDDLE AGED; MITOGENS; PLANT EXTRACTS; PLANTS, MEDICINAL;

EID: 0034812369     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(01)00319-1     Document Type: Article

References (23)

1. Direct activation of calcium-activated phospholipid-dependent protein kinase by tumor-promoting phorbol esters
2. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage
3. Transcription factors as targets for oxidative signalling during lymphocyte activation
4. Accessory cell dependence of lectin-induced proliferation of mouse T lymphocytes
5. An evaluation of the potency of Osbeckia octandra and melothria maderaspantana as antihepatotoxic agents
6. Fas and perforin pathways as major mechanisms of T-cell-mediated cytotoxicity
7. The immunomodulatory and antitumour activities of trichosanthin - An abortifacient protein isolated from tian-hua-fen (Trichosanthes kirilowii)
8. Role of Fas ligand in apoptosis induced by hepatitis C virus infection
9. Immunomodulatory activities of Cedrela lilloi and Trichilia elegans aqueous leaf extracts
10. Quantitation of microbicidal activity of mononuclear phagocytes: An in vitro technique
11. Polyphenols in chocolate, which have antioxidant activity, modulate immune functions in humans in vitro
12. Differential binding of two chicken beta-galactoside-specific lectins to homologous lymphocyte subpopulations and evidence for inhibitor activity of the dimeric lectin on stimulated T cells
13. Derivatives of gallic acid induce apoptosis in tumoral cell lines and inhibit lymphocyte proliferation
14. Immunomodulatory activity of three Sri-Lankan medicinal plants used in hepatic disorders
15. Protective effects of Osbeckia octandra against galactosamine and tert-butyl hydroperoxide induced hepatocyte damage
16. Phytogenic agents in the therapy of liver disease
17. Protective effects of Osbeckia octandra against paracetamol-induced liver injury
18. Antioxidant activity of Osbeckia aspera
19. A comparative study of the efficacy of Osbeckia octandra and Pavetta indica in the treatment of liver dysfunction
20. In vitro stimulation of human granulocytes and lymphocytes by pico- and femtogram quantities of cytostatic agents
21. Immunomodulatory and anti-tumour polysaccharides from medicinal plants