Enhancement of fluoroquinolone activity by C-8 halogen and methoxy moieties: Action against a gyrase resistance mutant of Mycobacterium smegmatis and a gyrase-topoisomerase iv double mutant of Staphylococcus aureus

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 10, 2001, Pages 2703-2709

  Lu, T ^a   Zhao, X ^a   Li, X ^a   Drlica Wagner, A ^a   Wang, J Y ^a   Domagala, J ^a   Drlica, K ^a  

^a PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 (3 METHYL 1 PIPERAZINYL) 4 OXO 3 QUINOLINECARBOXYLIC ACID; 8 BROMO 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 (3 METHYL 1 PIPERAZINYL) 4 OXO 3 QUINOLINECARBOXYLIC ACID; ANTIBIOTIC AGENT; BAY Y 3114; CIPROFLOXACIN; DNA; ENROFLOXACIN; MOXIFLOXACIN; PD 125232; PD 125275; PD 129603; PD 135432; PD 138124; PD 158804; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATE; BACTERIUM MUTANT; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM SMEGMATIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ANTI-INFECTIVE AGENTS; CIPROFLOXACIN; DNA GYRASE; DNA TOPOISOMERASE IV; HALOGENS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM SMEGMATIS; STAPHYLOCOCCUS AUREUS;

EID: 0034811655     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.10.2703-2709.2001     Document Type: Article

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