Molecular and functional analyses of the gene (eshA) encoding the 52-kilodalton protein of Streptomyces coelicolor A3(2) required for antibiotic production

Journal of Bacteriology

Volumn 183, Issue 20, 2001, Pages 6009-6016

  Kawamoto, S ^a   Watanabe, M ^a   Saito, N ^a   Hesketh, A ^a   Vachalova, K ^a   Matsubara, K ^a   Ochi, K ^a  

^a NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN ESHA; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ARTICLE; BACTERIAL GROWTH; DRUG MANUFACTURE; GENE MAPPING; GENETIC ANALYSIS; MOLECULAR BIOLOGY; MOLECULAR CLONING; MUTATION; MYCOBACTERIUM LEPRAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; STREPTOMYCES COELICOLOR; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANTHRAQUINONES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BLOTTING, SOUTHERN; CLONING, MOLECULAR; GENES, BACTERIAL; GENETIC COMPLEMENTATION TEST; MOLECULAR SEQUENCE DATA; MUTAGENESIS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; STREPTOMYCES; TRANSCRIPTION, GENETIC;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); EUKARYOTA; MYCOBACTERIUM LEPRAE; STREPTOMYCES COELICOLOR; STREPTOMYCES GRISEUS; UNCULTURED ACTINOMYCETE;

EID: 0034811047     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.20.6009-6016.2001     Document Type: Article

References (36)

1. The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation
2. Streptomyces
3. Regulation of bacterial antibiotic production
4. Cloning, sequence, and expression of the Drosophila cAMP-dependent protein kinase catalytic subunit gene
5. Induction of ppGpp synthesis in Streptomyces coelicolor A3(2) grown under conditions of nutritional sufficiency elicits actII-ORF4 transcription and actinorhodin biosynthesis
6. Molecular genetics of antibiotic formation
7. The major native proteins of the leprosy bacillus
8. cGMP-dependent protein kinase genes in Drosophila
9. Possible involvement of cAMP in aerial mycelium formation and secondary metabolism in Streptomyces griseus
10. Expression analysis of the ssgA gene product, associated with sporulation and cell division in Streptomyces griseus
11. Molecular analysis of the ribosomal L11 protein (rplK=relC) of Streptomyces griseus and identification of a deletion allele
12. Cloning and characterization of gentamicin-resistance genes from Micromonospora purpurea and Micromonospora rosea
13. The positions of the sigma-factor genes, whiG and sigF, in the hierarchy controlling the development of spore chains in the aerial hyphae of Streptomyces coelicolor A3(2)
14. Identification and characterization of a developmentally regulated protein, EshA, required for sporogenic hyphal branches in Streptomyces griseus
15. A relA/spoT homologous gene from Streptomyces coelicolor A3(2) controls antibiotic biosynthetic genes
16. Use of sodium trichloroacetate and mung bean nuclease to increase sensitivity and precitsion during transcript mapping
17. Decision phase regulation of streptomycin production in Streptomyces griseus
18. Genes encoded on a cyanobacterial plasmid that are transcriptionally regulated by sulfur availability and CysR
19. Two enzymes together capable of cysteine biosynthesis are encoded on a cyanobacterial plasmid
20. Extracellular complementation and the identification of additional genes involved in aerial mycelium formation in Streptomyces coelicolor
21. Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: Significance of the stringent response (ppGpp) and GTP content in relation to A-factor
22. Heterogeneity of ribosomal proteins among Streptomyces species and its application to identification
23. Streptomyces relC mutants with an altered ribosomal protein ST-L11 and genetic analysis of a Streptomyces griseus relC mutant
24. Molecular and functional analysis of the ribosomal L11 and S12 protein genes (rplK and rpsL) of Streptomyces coelicolor A3(2)
25. Molecular cloning and characterization of the obg gene of Streptomyces griseus in relation to the onset of morphological differentiation
26. An essential GTP-binding protein functions as a regulator for differentiation in Streptomyces coelicolor
27. A set of ordered cosmids amd a detailed genetic and physical map for the 8Mb Streptomyces coelicolor A3(2) chromosome
28. DNA sequencing with chain-terminating inhibitors
29. Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2)
30. Pleiotropic effects of cAMP on germination, antibiotic biosynthesis and morphological development in Streptomyces coelicolor
31. Transcriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecyl-prodigiosin in Streptomyces coelicolor A3(2)
32. Guanosine cyclic 3′, 5′-phosphate dependent protein kinase, a chimeric protein homologous with two separate protein families
33. Molecular and immunological analysis of the Mycobacterium avium homolog of the immunodominant Mycobacterium leprae 35-kilodalton protein
34. Characterization of the gene encoding the immunodominant 35 kDa protein of Mycobacterium leprae