The cyclooxygenase hydroperoxide product PGG2 activates synaptic nitric oxide synthase: A possible antioxidant response to membrane lipid peroxidation

Biochemical and Biophysical Research Communications

Volumn 286, Issue 2, 2001, Pages 235-238

  Foley, Timothy D ^a  

^a UNIVERSITY OF SCRANTON   (United States)

Author keywords

Lipid peroxidation; Nitric oxide synthase; Prostaglandin G2; Synaptosomal membranes

Indexed keywords

15 HYDROPEROXYARACHIDONIC ACID; ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; ARACHIDONIC ACID; HYDROGEN PEROXIDE; HYDROPEROXIDE; HYDROXYL GROUP; LIPID HYDROPEROXIDE; MEMBRANE LIPID; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN G2; PROSTAGLANDIN H2; PROSTAGLANDIN SYNTHASE; URATE;

ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CATALYST; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPTIC MEMBRANE;

EID: 0034810721     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5378     Document Type: Article

References (22)

1. Nitric oxide and lipid peroxidation
2. Interactions between nitric oxide and lipid oxidation pathways
3. Prostaglandin endoperoxide synthase: Structure and catalysis
4. Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis
5. Requirements for hydroperoxide by the cyclooxygenase and peroxidase activities of prostaglandin H synthase
6. Selective microdetermination of lipid hydroperoxides
7. +-ATPase ligand ouabain activate intracellular signaling enzymes
8. +-ATPase activity
9. A rapid method for the preparation of relatively pure metabolically competent synaptosomes from rat brain
10. Active transport of γ-aminobutyric acid by membrane vesicles isolated from rat brain
11. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation
12. Nitric oxide synthase activity in mitochondria
13. Measurement of protein using bicinchoninic acid
14. Changes in nitric oxide synthase activity during exposure to hydrogen peroxide in cultured endothelial cells
15. The effects of oxygen radicals on the activity of nitric oxide synthase and guanylate cyclase
16. Alteration of nitric oxide synthase activity upon oxidative stress in cultured retinal cells
17. Uric acid-iron ion complexes. A new aspect of the antioxidant functions of uric acid
18. Isolation of synaptic plasma membrane from brain by combined flotation-sedimentation density gradient centrifugation
19. Preparation and properties of mitochondria derived from synaptosomes
20. Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver
21. Production of nitric oxide by mitochondria