Estimating synaptic parameters from mean, variance, and covariance in trains of synaptic responses

Biophysical Journal

Volumn 81, Issue 4, 2001, Pages 1970-1989

  Scheuss, Volker ^a   Neher, Erwin ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

POSTSYNAPTIC RECEPTOR;

ALGORITHM; ARTICLE; CALCULATION; MODEL; PARAMETER; PLASTICITY; PRACTICE GUIDELINE; SYNAPSE; SYNAPTIC TRANSMISSION; SYSTEM ANALYSIS;

EID: 0034810689     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75848-1     Document Type: Article

References (52)

1. Intersynaptic diffusion of neurotransmitter
2. Quantal analysis of EPSCs recorded from small numbers of synapses in hippocampal cultures
3. Inhibitors of vesicle filling selectively affect high frequency transmission at striatal gabanergic synapses in vitro
4. Calcium influx and transmitter release in a fast CNS synapse
5. Variance analysis of excitatory postsynaptic potentials in cat spinal motoneurons during posttetanic potentiation
6. Unveiling synaptic plasticity: A new graphical and analytical approach
7. Quantal components of the endplate potential
8. Transporters buffer synaptically released glutamate on a submillisecond time scale
9. Heterogeneity of release probability, facilitation, and depletion at central synapses
10. A quantitative study of the end-plate potentials in isolated human muscle
11. Effects of variance in mini amplitude on stimulus-evoked release: A comparison of two models
12. Nonstationary noise analysis and application to patch clamp recordings
13. Transmission at a central inhibitory synapse. II. Quantal description of release, with a physical correlate for binomial n
14. The one-vesicle hypothesis and multivesicular release
15. Efficacy and stability of quantal GABA release at a hippocampal interneuron-principal neuron synapse
16. 2+-triggered fusion and recycling of synaptic vesicles in vivo
17. Cyclic AMP induces functional presynaptic boutons in hippocampal CA3-CA1 neuronal cultures
18. Implications of all-or-none synaptic transmission and short-term depression beyond vesicle depletion: A computational study
19. The statistics of transmitter release at chemical synapses
20. Heterogeneous release properties of visualized individual hippocampal synapses
21. 2+ microdomains: New tools for understanding their roles in neurotransmitter release
22. Combining deconvolution and noise analysis for the estimation of transmitter release rates at the Calyx of Held
23. Release probability modulates short-term plasticity at a rat giant terminal
24. Least squares when both variables have uncertainties
25. Delayed clearance of transmitter and the role of glutamate transporters at synapses with multiple release sites
26. Direct measurement of AMPA receptor desensitization induced by glutamatergic synaptic transmission
27. The binomial model in fluctuation analysis of quantal neurotransmitter release
28. Quantal analysis of synaptic potentials in neurons of the central nervous system
29. Postsynaptic expression of long-term potentiation in the rat dentate gyrus demonstrated by variance-mean analysis
30. Target-cell-specific facilitation and depression in neocortical circuits
31. Nonuniform probability of glutamate release at a hippocampal synapse
32. Quantitative relationship between transmitter release and calcium current at the Calyx of Held synapse
33. Quantitative ultrastructural analysis of hippocampal excitatory synapses
34. The variance of sodium current fluctuations at the node of Ranvier
35. Locus of frequency-dependent depression identified with multiple-probability fluctuation analysis at rat climbing fibre-Purkinje cell synapses
36. Presynaptic determinants of synaptic efficacy in hippocampal pyramidal neurons
37. Multivesicular release from excitatory synapses of cultured hippocampal neurons
38. Desensitization of AMPA receptors upon multiquantal neurotransmitter release
39. Simple stochastic models for the release of quanta of transmitter from a nerve terminal
40. Presynaptic depression at a calyx synapse: The small contribution of metabotropic glutamate receptors
41. Properties and plasticity of paired-pulse depression at a central synapse
42. Quantal analysis of synaptic transmission
43. Nonuniform release probabilities underlie quantal synaptic transmission at a mammalian excitatory central synapse
44. 2+-dependent vesicle pool dynamics and short term synaptic depression
45. The reduced release probability of releasable vesicles during recovery from short-term synaptic depression
46. Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity
47. Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents
48. Changes in the statistics of transmitter release during facilitation
49. Short-term synaptic plasticity
50. Calcium- and activity-dependent synaptic plasticity