Leber hereditary optic neuropathy, progressive visual loss, and multiple-sclerosis-like symptoms

American Journal of Ophthalmology

Volumn 132, Issue 4, 2001, Pages 591-593

  Tran, Mai ^a   Bhargava, Ravi ^a   MacDonald, Ian M ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; HEREDITARY OPTIC ATROPHY; HUMAN; MALE; MULTIPLE SCLEROSIS; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; VISUAL ACUITY; VISUAL FIELD; VISUAL IMPAIRMENT;

ADULT; DISEASE PROGRESSION; DNA, MITOCHONDRIAL; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MITOCHONDRIA; MULTIPLE SCLEROSIS; MUTATION; OPTIC ATROPHIES, HEREDITARY; VISION DISORDERS;

EID: 0034810578     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9394(01)01045-5     Document Type: Article

References (5)

1. Wallace DC, Singh G, Lott MT, et al. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 1988;242:1427-1430.
2. Harding AE, Sweeney MG, Miller DH, et al. Occurrence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation. Brain 1992;115:979-989.
3. Riordan-Eva P, Harding AE. Leber's hereditary optic neuropathy: the clinical relevance of different mitochondrial DNA mutations. J Med Genet 1995;32:81-87.
4. Newman NJ, Lott MT, Wallace DC. The clinical characteristics of pedigrees of Leber's hereditary optic neuropathy with the 11778 mutation. Am J Ophthalmol 1991;111:750-762.
5. Olsen NK, Hansen AW, Nørby S, et al. Leber's hereditary optic neuropathy associated with a disorder indistinguishable from multiple sclerosis in a male harbouring the mitochondrial DNA 11778 mutation. Acta Neurol Scand 1995;91:326-39.