Posttranscription initiation control of tryptophan metabolism in Bacillus subtilis by the trp RNA-binding attenuation protein (TRAP), anti-TRAP, and RNA structure

Journal of Bacteriology

Volumn 183, Issue 20, 2001, Pages 5795-5802

  Babitzke, P ^a   Gollnick, P ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID METABOLISM; BACILLUS SUBTILIS; BINDING SITE; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; RNA STRUCTURE; SHORT SURVEY; TRANSCRIPTION INITIATION;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; BASE SEQUENCE; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OPERON; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; RNA, BACTERIAL; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRYPTOPHAN;

BACILLUS SUBTILIS;

EID: 0034810138     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.20.5795-5802.2001     Document Type: Short Survey

References (46)

1. Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA
2. The structure of the trp RNA attenuation protein
3. Regulation of tryptophan biosynthesis: Trp-ing the TRAP or how Bacillus subtilis reinvented the wheel
4. Reconstitution of Bacillus subtilis trp attenuation in vitro with TRAP, the trp RNA-binding attenuation protein
5. Structural features of L-tryptophan required for activation of TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis
6. TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis, is a toroid-shaped molecule that binds transcripts containing GAG or UAG repeats separated by two nucleotides
7. TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis, is a multisubunit complex that appears to recognize G/UAG repeats in the trpEDCFBA and trpG transcripts
8. Interaction of the trp RNA-binding attenuation protein (TRAP) of Bacillus subtilis with RNA: Effects of the number of GAG repeats, the nucleotides separating adjacent repeats, and RNA secondary structure
9. The mtrAB operon of Bacillus subtilis encodes GTP cyclohydrolase I (MtrA), an enzyme involved in folic acid biosynthesis, and MtrB, a regulator of L-tryptophan biosynthesis
10. Kinetic and thermodynamic analysis of the interaction between TRAP (trp RNA-binding attenuation protein) of Bacillus subtilis and trp leader RNA
11. The trp RNA-binding attenuation protein (TRAP) from Bacillus subtilis binds to unstacked trp leader RNA
12. Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus
13. The trp RNA-binding attenuation protein (TRAP) regulates the steady-state levels of transcripts of the Bacillus subtilis folate operon
14. trp-RNA binding attenuation protein-mediated long-distance RNA refolding regulates translation of trpE in Bacillus subtilis
15. trp RNA-binding attenuation protein-5′ stem-loop RNA interaction is required for proper transcription attenuation control of the Bacillus subtilis trpEDCFBA operon
16. The trp-RNA binding attenuation protein regulates TrpG synthesis by binding to the trpG ribosome binding site of Bacillus subtilis
17. Probing the TRAP-RNA interaction with nucleoside analogs
18. The mechanism of RNA binding to TRAP: Initiation and cooperative interactions
19. The TRAP-like SplA protein is a trans-acting negative regulator of spore photoproduct lyase synthesis during Bacillus subtilis sporulation
20. Regulation of the Bacillus subtilis trp operon by an RNA-binding protein
21. The mtr locus is a two gene operon required for transcription attenuation in the trp operon of Bacillus subtilis
22. Control of transcription termination in prokaryotes
23. Biosynthesis of aromatic amino acids
24. Nucleotide sequence of the Bacillus subtilis tryptophan operon
25. The mtrB gene of Bacillus pumilus encodes a protein with sequence and functional homology to the trp RNA-binding attenuation protein (TRAP) of Bacillus subtilis
26. Regulation of a common amidotransferase subunit
27. cis-acting sites in the transcript of the Bacillus subtilis trp operon regulate expression of the operon
28. Transcription attenuation
29. A temperature-sensitive trpS mutation interferes with TRAP regulation of trp gene expression in Bacillus subtilis
30. Translational control of prokaryotic gene expression
31. trp RNA-binding attenuation protein (TRAP)-trp leader RNA interactions mediate translational as well as transcriptional regulation of the Bacillus subtilis trp operon
32. Translational coupling during expression of the tryptophan operon of Escherichia coli
33. MtrB from Bacillus subtilis binds specifically to trp leader RNA in a tryptophan dependent manner
34. A Bacillus subtilis gene of previously unknown function, yhaG, is translationally regulated by trypto-phan-activated TRAP and appears to be involved in tryptophan transport
35. Trp charging and regulates expression of the genes of tryptophan biosynthesis
36. Characterization of the Bacillus subtilis tryptophan promoter region
37. Novel form of transcription attenuation regulates expression of the Bacillus subtilis tryptophan operon
38. An apparent Bacillus subtilis folic acid biosynthetic operon containing pab, an amphibolic trpG gene, a third gene required for synthesis of para-aminobenzoic acid, and the dihydropteroate synthase gene
39. Temperature-induced derepression of tryptophan biosynthesis in a tryptopbanyl-transfer ribonucleic acid synthetase mutant of Bacillus subtilis
40. A 5′ RNA stem-loop participates in the transcription attenuation mechanism that controls expression of the Bacillus subtilis trpEDCFBA operon
41. Inibition of TRAP, the B. subtilis trp RNA-binding attenuation protein, by the anti-TRAP protein, AT
42. RNA structure inhibits the TRAP (trp RNA-binding attenuation protein)-RNA interaction
43. Effects of mutations in the L-tryptophan binding pocket of the trp RNA-binding attenuation protein of Bacillus subtilis
44. Expression of the Bacillus subtilis trpEDCFBA operon is influenced by translational coupling and Rho termination factor
45. Translation of trpG in Bacillus subtilis is regulated by the trp RNA-binding attenuation protein (TRAP)
46. Alanine-scanning mutagenesis of Bacillus subtilis trp RNA-binding attenuation protein (TRAP) reveals residues involved in tryptophan binding and RNA binding