Clinical study of a monophasic pill containing 20 μg ethinylestradiol and 150 μg desogestrel in Thai women

Journal of the Medical Association of Thailand

Volumn 84, Issue SUPPL. 1, 2001, Pages

  Jaisamrarn, Unnop ^a   Reinprayoon, Damrong ^a   Virutamasen, Pramuan ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Desogestrel; Oral contraceptive; Thai women

Indexed keywords

DESOGESTREL PLUS ETHINYLESTRADIOL; ORAL CONTRACEPTIVE AGENT;

ADULT; ARTICLE; BLOOD PRESSURE MONITORING; BODY WEIGHT; CHLOASMA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FAMILY PLANNING; FEMALE; HUMAN; MAJOR CLINICAL STUDY; NAUSEA; ORAL CONTRACEPTION; THAILAND; VAGINA BLEEDING; VERTIGO;

ADOLESCENT; ADULT; CONTRACEPTIVES, ORAL, COMBINED; DESOGESTREL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHINYL ESTRADIOL; EVALUATION STUDIES; FEMALE; HUMANS; PREGNANCY; PREGNANCY RATE; SENSITIVITY AND SPECIFICITY; THAILAND; TREATMENT OUTCOME;

EID: 0034808943     PISSN: 01252208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jick H, Dinan B, Rothman KJ. Oral contraceptives and nonfatal myocardial infarction. JAMA 1978; 239: 1403-6.
2. Maguire MG, Tomascia I, Sartwell PE, Stolley PD, Tookman MS. Increase risk of thrombosis due to oral contraceptives. Am J Epidemiol 1979; 110: 188-95.
3. Stadel BV. Oral contraceptives 'and cardiovascular disease (first of two parts). N Engl J Med 1981; 305: 612-8.
4. Mammen EF. Oral contraceptives and blood coagulation : a critical review. Am J Obstet Gynecol 1982; 142: 781-90.
5. Wahl P, Walden C, Knopp R, et al. Effect of estrogen/progestin potency on lipid/lipoprotein cholesterol. New Engl J Med 1983; 308: 862-7.
6. Cauley JA. Menopausal estrogen use, high den-sity lipoprotein cholesterol and liver function. Atherosclerosis 1983; 49: 31-9.
7. Krauss RM, Lindgren FT, Wingerd J, et al. Effects of estrogens and progestins on high density lipoproteins. Lipids 1979; 14: 113-8.
8. Solyom A. Effects of androgens on serum lipids and lipoproteins. Lipids 1972; 7: 100-5.
9. Stolley PD, Tonascia JA, Tockman MS, Sartwell PE, Rutledge AH, Jacobs MP. Thrombosis with low - estrogen oral contraceptives. Am J Epidemiol 1975; 102: 197-08.
10. Meade TW, Greenberg G, Thompson SG. Progestogens and cardiovascular reactions associated with oral contraceptives and a comparison of the safety of 50 - and 30 - microgram oestrogen preparations. BMJ 1980; 280: 1157-61.
11. Stadel BV. Oral contraceptives and cardiovascular disease (second of two parts). N Engl J Med 1981; 305: 672-7.
12. Nevinny - Stickel J. German trial of an oral contraceptive containing 0.015 mg desogestrel plus 0.020 mg ethinylestradiol. Acta Obstet Gynecol Scand 1987; 144 (Suppl): 19-21.
13. Tuimala R. Effects of the oral contraceptive combination 0.015 mg desogestrel + 0.020 mg ethinylestradiol an serum lipids, SHBG, glycosylated proteins and plasma antithrombin III activity in healthy women. Acta Obstet Gynecol Scand 1987; 114 (Suppl): 37-9.
14. Falsetti L. A new low - dose estrogen oral contraceptive combination : effects on endocrine parameters and lipid status. Contraception 1987; 36: 489-97.
15. Fioretti P. Clinical and metabolic study of a new pill containing 20 μg ethinylestradiol plus 0.150 μg desogestrel. Contraception 1987; 35: 229-43.
16. van den Ende A. Effects of the oral contraceptive combination 0.150 mg desogestrel plus 0.20 mg ethinylestradiol on carbohydrate metabolism in healthy female volunteers. Acta Obstet Gynecol Scand 1987; 144(Suppl): 29-32.
17. Lammers P, op ten Berg M. Phase III clinical trial with a new oral contraceptive containing 150 pg desogestrel and 20 μg ethinylestradiol. Acta Obstet Gynecol Scand 1991; 70: 497-00.
18. Fotherby K. Clinical experience and pharmacological effects of an oral contraceptive containing 20 μg oestrogen. Contraception 1992; 46: 477-88.
19. Belsey EM, Machin D, Arcangues C. The analysis of vaginal bleeding patterns induced by fertility regulating methods. Contraception 1986; 34: 253-60.
20. Viinikka L, Hirvonen E, Ylikorkala O, et al. Ovulation inhibition by a new low - dose progestogen. Contraception 1977; 16: 51-9.
21. Trussell J, Kost K. Contraceptive failure in the United States : A critical review of the literature. Stud Fam Plann 1987; 18: 237-83.