Prediction of lidocaine tissue concentrations following different dose regimes during cardiac arrest using a physiologically based pharmacokinetic model

Resuscitation

Volumn 50, Issue 3, 2001, Pages 331-340

  Grillo, Joseph A ^a   Venitz, Jürgen ^b   Ornato, Joseph P ^c  

^a SHENANDOAH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiopulmonary resuscitation; Heart arrest; Lidocaine; Pharmacokinetics; Resuscitation

Indexed keywords

LIDOCAINE;

ARTICLE; COMPARATIVE STUDY; DISEASE SIMULATION; DOSE CALCULATION; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG BRAIN LEVEL; DRUG TISSUE LEVEL; HEART ARREST; MODEL; ORGAN AND TISSUE BLOOD FLOW; ORGAN BLOOD FLOW; PARTITION COEFFICIENT; PREDICTION; PRIORITY JOURNAL;

ALGORITHMS; ANESTHETICS, LOCAL; HEART ARREST; HUMANS; LIDOCAINE; MODELS, CARDIOVASCULAR; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

EID: 0034807781     PISSN: 03009572     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9572(01)00355-0     Document Type: Article

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