Clonidine attenuates naloxone-induced opioid-withdrawal syndrome in cholestatic mice

Pharmacology and Toxicology

Volumn 89, Issue 3, 2001, Pages 129-132

  Dehpour, Ahmad Reza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; NALOXONE; OPIATE; YOHIMBINE;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE DUCT; CHOLESTASIS; CONTROLLED STUDY; DISEASE SEVERITY; DRUG DEPENDENCE; MALE; MOUSE; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; WITHDRAWAL SYNDROME;

EID: 0034807551     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0773.2001.d01-146.x     Document Type: Article

References (5)

1. Aghajanian, G. K.: Tolerance of locus coeruleus to morphine and suppression of withdrawal response by clonidine. Nature 1978, 276, 186-188.
2. Akbarloyshbgahi, N., M. Samini, A. R. Dehpour & M. A. Arad: Clonidine attenuates withdrawal signs in acute cholestatic mice. Nawiyn-Schmiedeberg Arch. Pharmacol 1998, 358, Iss 1, pp 138 [abstract].
3. Bergasa, N. V, R. B. Rothman, J. Vergalla, H. Xu, M. G. Swain & E. A. Jones: Central mu-opioid receptors are down-regulated in a rat model of cholestasis. J. Hepatol. 1992, 15, 220-224.
4. Bonjianni, E, V. Carla, F. Moroni & D. E. Pellegrini-Giampietro: Calcium channel inhibitors suppress the morphine withdrawal syndrome in rats. Brit. J. Pharmacol. 1982, 88, 561-567.
5. Charney, D. S., D. E. Redmond, M. P. Galloway, H. D. Kleber, G. R. Heninger, M. Murberg & R. H. Roth: Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: Evidence for noradrenergic hyperactivity. Life Sci. 1984, 35, 1263-1272.