Synthesis and application of Fmoc-His(3-Bum)-OH

Journal of Peptide Science

Volumn 7, Issue 9, 2001, Pages 502-510

  Mergler, M ^a   Dick, F ^a   Sax, B ^a   Schwindling, J ^a   Vorherr, Th ^a  

^a Bachem Holding AG   (Switzerland)

Author keywords

Histidine; im Bum protection; Racemization; SPPS

Indexed keywords

9 FLUORENYLMETHYL CHLOROFORMATE; FORMALDEHYDE; HISTIDINE DERIVATIVE; METHOXYAMINE; PEPTIDE;

ARTICLE; CONTROLLED STUDY; ESTERIFICATION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; RACEMIC MIXTURE;

AMINO ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUORENES; HISTIDINE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; PEPTIDE BIOSYNTHESIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0034807299     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.345     Document Type: Article

References (15)

1. Further studies on the protection of histidine side chains in peptide synthesis: The use of the benzyloxymethyl group
2. Acid-labile histidine side-chain protection: The N(π)-t-butoxymethyl group
3. Im-Trityl protection of histidine
4. t-Butyl chloromethyl ether
5. Anchoring of Fmoc amino acids to hydroxymethyl resins
6. Detection of secondary amines on solid phase
7. Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
8. A new micro-test for the detection of incomplete coupling reactions in solid-phase peptide synthesis using 2,4,6-trinitrobenzene-sulphonic acid
9. The regiospecific alkylation of histidine side chains
10. α9-fluorenylmethyloxycarbonyl amino acids to alkoxybenzyl alcohol type resins
11. An improved method for anchoring of 9-fluorenylmethoxycarbonyl-amino acids to 4-alkoxybenzyl alcohol resins
12. Synthesis and application of a novel coupling reagent, ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate
13. Racemisation studies of a novel reagent for solid-phase peptide synthesis
14. New coupling reagents in peptide chemistry
15. im-benzyloxymethyl group during synthesis of peptides containing cysteinyl residue at the N-terminus