A novel secreted tumor antigen with a glycosylphosphatidylinositol-anchored structure ubiquitously expressed in human cancers

Biochemical and Biophysical Research Communications

Volumn 285, Issue 2, 2001, Pages 235-243

  Onda, Haruo ^a   Ohkubo, Shoichi ^a   Shintani, Yasushi ^a   Ogi, Kazuhiro ^a   Kikuchi, Kuniko ^a   Tanaka, Hideyuki ^a   Yamamoto, Koji ^a   Tsuji, Isamu ^a   Ishibashi, Yoshihiro ^a   Yamada, Takao ^a   Kitada, Chieko ^a   Suzuki, Nobuhiro ^a   Sawada, Hidekazu ^a   Nishimura, Osamu ^a   Fujino, Masahiko ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

ALCAN; GPI anchored protein; Tumor antigen; Tumor marker; Tumor specific gene

Indexed keywords

AMINO ACID; GENE PRODUCT; GLYCOSYLPHOSPHATIDYLINOSITOL; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE PROTEIN; PROTEIN ALCAN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER; CANCER CELL; CARBOXY TERMINAL SEQUENCE; CHROMOSOME 6; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MAJOR HISTOCOMPATIBILITY COMPLEX; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

EID: 0034806264     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5149     Document Type: Article

References (32)

1. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes
2. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
3. The role of PSA and percent free PSA for staging and prognosis prediction in clinically localized prostate cancer
4. Human prostatic acid phosphatase has phosphotyrosyl protein phosphatase activity
5. The use of serologic tumor markers in gastrointestinal malignancies
6. The value of tumor markers in colorectal cancer
7. Characterization of human colon cancer antigens recognized by autologous antibodies
8. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
9. Serum CA 15.3, CEA and ESR pattern in breast cancer
10. Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: Characterization of tissue-specific ING1 transcripts and a homologue gene
11. Clinical tumour markers in ovarian cancer
12. Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma
13. The makings of a tumor rejection antigen
14. New paths in human cancer serology
15. Determinants for the establishment of permanent tissue culture lines from human gliomas
16. Single-step method of RNA isolation by acid guanidinium thioisocyanate - Phenolchloroform extraction
17. A sensitive sandwich-enzyme immunoassay for human endothelin
18. A new technique for the assay of infectivity of human adenovirus 5 DNA
19. Expression of the PACAP gene in a human neuroblastoma cell line: cDNA cloning and analysis of the upstream regulatory region
20. Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: A novel family encodes cell surface proteins sharing partial homology with MHC class I molecules
21. "Both man & bird & beast": Comparative organisation of MHC genes
22. Human neoplasms elicit multiple specific immune responses in the autologous host
23. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
24. Mutational analysis of the COOH-terminal hydrophobic domain of bovine liver 5′-nucleotidase as a signal for glycosylphosphatidylinositol (GPI) anchor attachment
25. Biosynthesis of glycosylphosphatidylinositol (GPI)-anchored membrane proteins in intact cells: Specific amino acid requirements adjacent to the site of cleavage and GPI attachment
26. Cellular, glycosylphosphatidylinositol-specific phospholipase D regulates urokinase receptor shedding and cell surface expression
27. Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer
28. Immune evasion of tumor cells using membrane-bound complement regulatory proteins
29. A functional analysis of recombinant soluble CD46 in vivo and a comparison with recombinant soluble forms of CD55 and CD35 in vitro
30. Melamona cells constitutively release an anchor-positive soluble form of protectin (sCD59) that retains functional activities in homologous complement-mediated cytotoxicity
31. Identification of a gene coding for a new squamous cell carcinoma antigen recognized by the CTL
32. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor