Cloning of full-length genomic DNA encoding human FcεRI α-chain and its transcriptional regulation

Biochemical and Biophysical Research Communications

Volumn 284, Issue 4, 2001, Pages 1056-1064

  Nishiyama, Chiharu ^a,b   Hasegawa, Masanari ^a   Nishiyama, Makoto ^c   Takahashi, Kyoko ^b   Yokota, Toyokazu ^b   Okumura, Ko ^a   Ra, Chisei ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b ASAHI BREWERIES LTD   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Fc RI chain; Genomic DNA; Promoter

Indexed keywords

DNA; FC RECEPTOR; IMMUNOGLOBULIN E RECEPTOR; NUCLEAR FACTOR;

ALPHA CHAIN; ARTICLE; ELECTROPHORETIC MOBILITY; EXON; HUMAN; HUMAN CELL; INTRON; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; TRANSCRIPTION REGULATION;

EID: 0034805397     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5079     Document Type: Article

References (28)

1. New nomenclauture for the Reth motif (or ARH1/TAM/ARAM/YXXL)
2. Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor
3. Complete structure of the mouse mast cell receptor for IgE (FcεRI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells
4. A single amino acid in the glycosylphosphatidylinositol attachment domain determines the membrane topology of FcγRIII
5. Association of the high-affinity receptor for IgG (FcγRI) with the γ subunit of the IgE receptor
6. Association of IgA-Fc receptors (FcαR) with FcεRIγ2 subunits in U937 cells
7. Family of disulfide-linked dimers containing the ζ and η chains of the T-cell receptor and γ chain of Fc receptors
8. T-cell and basophil activation through the cytoplasmic tail of T-cell receptor ζ family proteins
9. Structure-function relationships in the mast cell high affinity receptor for IgE: Role of the cytoplasmic domains and of the β subunit
10. The FcεRIβ subunit functions as an amplifier of FcεRIγ-mediated cell activation signals
11. Allergy-associated FcRβ is a molecular amplifier of IgE- and IgG-mediated in vivo responses
12. Expression of high-affinity binding of human immunoglobulin E by transfected cells
13. A second amplifier function for the allergy-associated FcεRI-β subunit
14. The α subunit of the human IgE receptor (FcεRI) is sufficient for high affinity IgE binding
15. Characterization of truncated α chain products from human, rat and mouse high affinity receptor for immunoglobulin E
16. Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor a chain gene
17. Induction of the high-affinity IgE receptor (FcεRI) on human mast cells by IL-4
18. Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the FcεRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells
19. Effect of recombinant human IL-4 on tryptase, chymase, and Fcε receptor type I expression in recombinant human stem cell factor-rependent fetal liver-derived human mast cells
20. IL-4 enhances proliferation and mediator release in mature human mast cells
21. IL-4 upregulates FcεRI α-chain messenger RNA in eosinophils
22. Modulation of high-affinity IgE receptor expression in blood monocytes: Opposite effect of IL-4 and glucocorticoids
23. Human and rat mast cell high-affinity immunoglobulin E receptors: Characterization of purative α-chain gene products
24. Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor
25. Characterization of the gene for the human high affinity IgE receptor (FcεRI) α-chain
26. The transcription factors Elf-1 and GATA-1 bind to cell-specific enhancer elements of human high-affinity IgE receptor α-chain gene
27. A complex composed of USF1 and USF2 activates the human FcεRI α chain expression via CAGCTG element in the first intron
28. Splice isoforms of transcription factor Elf-1 affecting its regulatory function in transcription. Molecular cloning of rat Elf-1