Heat shock restores insulin secretion after injury by nitric oxide by maintaining glucokinase activity in rat islets

Biochemical and Biophysical Research Communications

Volumn 284, Issue 1, 2001, Pages 20-25

  Takeda, Tomomi ^a   Tsuura, Yoshiyuki ^a   Fujita, Jun ^a   Fujimoto, Shimpei ^a   Mukai, Eri ^a   Kajikawa, Mariko ^a   Hamamoto, Yoshiyuki ^a   Kume, Makoto ^a   Yamamoto, Yuzo ^a   Yamaoka, Yoshio ^a   Yamada, Yuichiro ^a   Seino, Yutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Heat shock; Insulin secretion; Interleukin 1 ; Islets; Nitric oxide

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOKINASE; GLUCOSE; GLYCERALDEHYDE; HEXANOIC ACID DERIVATIVE; INSULIN; INTERLEUKIN 1BETA; NITRIC OXIDE; OXOISOCAPROIC ACID; POTASSIUM CHLORIDE; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE UTILIZATION; HEAT SHOCK; IN VITRO STUDY; INSULIN RELEASE; MALE; NONHUMAN; OXIDATIVE STRESS; PANCREAS INJURY; PANCREAS ISLET CELL; PRIORITY JOURNAL; RAT;

EID: 0034805145     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4933     Document Type: Article

References (35)

1. Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa
2. In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat
3. Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1β-induced impaired beta-cell function
4. Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro
5. Heat shock protein hsp70 overexpression confers resistance against nitric oxide
6. Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets
7. Heat treatment induces an increase in intracellular cyclic AMP content in human epidermoid A-431 cells
8. Modification of rat thymocyte membrane properties by hyperthermia and ionizing radiation
9. Overexpression of HSP-70 inhibits the phosphorylation of HSF1 by activating protein phosphatase and inhibiting protein kinase C activity
10. 2+ exchange in human epidermoid A 431 cells
11. Characterization of intra cellular calcium pools and their desensitization in thermotolerant cells
12. G-monomethyl-L-arginine
13. Interleukin-1β-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells
14. Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation
15. Interleukin-1β inhibits glucokinase activity in clonal HIT-T15 beta-cells
16. Interleukin-1 reduces the glycolytic utilization of glucose by pancreatic islets and reduces glucokinase mRNA content and protein synthesis by a nitric oxide-dependent mechanism
17. Inhibitory effects of streptozotocin, tumor necrosis factor-α, and interleukin-1β on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase
18. Characterization of expression of phosphofructokinase isoforms in isolated rat pancreatic islets and purified beta cells and cloning and expression of the rat phosphofructokinase-A isoform
19. + channels through suppression of phosphofructokinase activity and inhibits glucose-induced insulin release in pancreatic beta cells
20. Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression of phosphofructokinase activity in pancreatic islets
21. Interleukin-1β-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase
22. ATP channel
23. Interleukin-1β effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion
24. Interleukin-1β induces an early decrease in insulin release, (pro) insulin biosynthesis and insulin mRNA in mouse pancreatic islets by a mechanism dependent on gene transcription and protein synthesis
25. Oxygen free radical scavengers protect rat islet cells from damage by cytokines
26. Isolation of rat pancreatic islets by ductal injection of collagenase
27. 2+ sensitivity in beta-cells
28. Augmentation of basal insulin release from rat islets by preexposure to a high concentration of glucose
29. The pentose cycle and insulin release in mouse pancreatic islets
30. Control of glucose metabolism in pancreatic beta-cells by glucokinase, hexokinase, and phosphofructokinase
31. Protein measurement with the folin phenol reagent
32. Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis
33. 2+ uptake by islets of Langerhans
34. Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM
35. Interleukin 1β induces diabetes and fever in normal rats by nitric oxide via induction of different nitric oxide syntheses