Fifty-seven-kDa protein in royal jelly enhances proliferation of primary cultured rat hepatocytes and increases albumin production in the absence of serum

Biochemical and Biophysical Research Communications

Volumn 282, Issue 4, 2001, Pages 865-874

  Kamakura, Masaki ^a   Suenobu, Noriko ^a   Fukushima, Makoto ^a  

^a National Institute of Health Sciences   (Japan)

Author keywords

57 kDa protein; Albumin production; DNA synthesis; Hepatocyte proliferation; Mitogen; Royal jelly

Indexed keywords

ALBUMIN; BOVINE SERUM ALBUMIN; MITOGENIC AGENT; PROTEIN; ROYAL JELLY; TRYPSIN;

ADOLESCENT; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DENSITY; CELL PROLIFERATION; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DNA SYNTHESIS; LIVER CELL; LIVER PROTECTION; LIVER REGENERATION; MALE; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; RAT; STORAGE; TEMPERATURE;

EID: 0034805081     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4656     Document Type: Article

References (59)

1. Regulation of liver growth. Historical perspective and future directions
2. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal
3. Cell culture studies using extracts of extracellular matrix to study growth and differentiation in mammalian cells
4. Hepatocyte proliferation in culture
5. Control of hepatocyte proliferation in vitro
6. Hormonal stimulation of DNA synthesis in primary cultures of adult rat hepatocytes
7. Biochemical functions of adult rat hepatocytes in primary culture
8. Hormonal regulation of DNA synthesis in primary cultures of adult rat hepatocytes: Action of glucagon
9. DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: Effects of epidermal growth factor, insulin, glucagon and cyclic-AMP
10. Emerging multipotent aspects of hepatocyte growth factor
11. A high concentration of pyruvate is essential for survival and DNA synthesis in primary cultures of adult hepatocytes in a serum-free medium
12. Pyruvate promotion of DNA synthesis in serum-free primary cultures of adult rat hepatocytes
13. Multiple cell cycles occur in rat hepatocytes cultured in the presence of nicotinamide and epidermal growth factor
14. Long-term maintenance of functional rat hepatocytes in primary culture by additions of pyruvate and various hormones
15. Nicotinamide prolongs survival of primary cultured hepatocytes without involving loss of hepatocytes-specific functions
16. Honey bee nutrition
17. Electrophoretic components of the proteins in honeybee larval food
18. Chemical composition of royal jelly
19. Comparative studies on chemical composition of honey, royal jelly and pollen loads
20. Composition of freshly harvested and commercial royal jelly
21. Biochemical studies on vasodilative factor in royal jelly
22. A potent antibacterial protein in royal jelly
23. Antitumor effect of royal jelly
24. Activity of 10-hydroxydecenoic acid from royal jelly against experimental leukemia and ascitic tumors
25. Studies on the in vitro antitumor activity of fatty acid I. 10-Hydroxy-2-decenoic acid from royal jelly
26. Studies on the in vitro antitumor activity of fatty acid IV. The esters of acids closely related to 10-hydroxy-2-decenoic acid from royal jelly against transplantable mouse leukemia
27. Augmentation of wound healing by royal jelly (RJ) in streptozotocin-diabetic rats
28. The effect of royal jelly on blood lipids in atheromatic subjects
29. The effect of course-wise administration of different doses of Apilak upon some lipid metabolism indices
30. Effect of royal jelly on serum lipids in experimental animals and humans with atherosclerosis
31. Effect of royal jelly on experimental hypercholesterolemia in rabbits
32. The effect of lecithin supplementation on the biochemical profile and morphological changes in the liver of rats fed different animal fats
33. Effect of royal jelly on development of genital organs in male mice
34. Stimulation of cell growth in the U-937 human myeloid cell line by honey royal jelly protein
35. Storage-dependent degradation of 57-kDa protein in royal jelly: A possible marker for freshness
36. Preparation of isolated liver cells
37. Density-dependent proliferation of adult rat hepatocytes in primary culture induced by epidermal growth factor is potentiated by cAMP-elevating agents
38. Protein measurement with the Folin phenol reagent
39. Electrophoresis of proteins
40. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
41. Hepatocyte proliferation in vitro: Its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix
42. Cell density-dependent DNA fragmentation and its suppression by heparin in primary culture of adult rat hepatocytes
43. Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: Protection with antioxidants and glutamate receptor antagonist
44. Serum deprivation-induced apoptosis in cultured porcine granulosa cells is characterized by increased expression of p53 protein, Fas antigen and Fas ligand and by decreased expression of PCNA
45. Serum withdrawal-induced apoptosis in thyroid cells is caused by loss of fibronectin-integrin interaction
46. Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor
47. Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture
48. Apoptosis of serum-free C2.8 mouse embryo hepatocytic cells caused by hepatocyte growth factor deprivation
49. Effect of 350 kDa glycoprotein in royal jelly on primary culture of rat hepatocytes
50. Cell density-dependent regulation of albumin synthesis and DNA synthesis in rat hepatocytes by hepatocyte growth factor
51. Liver regeneration studies with rat hepatocytes in primary culture
52. Density-dependent growth control of adult rat hepatocytes in primary culture
53. Reciprocal modulation of growth and differentiated functions of mature rat hepatocytes in primary culture by cell-cell contact and cell membranes
54. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
55. The effect of human milk on DNA synthesis of neonatal rat hepatocytes in primary culture
56. Enhancement of albumin production by hepatocyte growth factor in rat hepatocytes: Distinction in mode of action from stimulation of DNA synthesis
57. Hepatocyte growth factor stimulates liver regeneration and elevates blood protein level in normal and partially hepatectomized rats
58. Transforming growth factor α may be a physiological regulator of liver regeneration by means of an autocrine mechanism
59. Heparin-binding growth factor type 1 (acidic fibroblast growth factor): A potential biphasic autocrine and paracrine regulator of hepatocyte regeneration