Low-dose dexamethasone augments the ovarian response to exogenous gonadotrophins leading to a reduction in cycle cancellation rate in a standard IVF programme

Human Reproduction

Volumn 16, Issue 9, 2001, Pages 1861-1865

  Keay, S D ^a   Lenton, E A ^b   Cooke, I D ^b   Hull, M G R ^c   Jenkins, J M ^c  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Dexamethasone co treatment; Gonadotrophins; IVF; Ovarian stimulation; Poor response

Indexed keywords

CHORIONIC GONADOTROPIN; DEXAMETHASONE; FOLLITROPIN; GONADORELIN DERIVATIVE; PLACEBO; UROFOLLITROPIN;

ADULT; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE INFERTILITY; FERTILIZATION; FERTILIZATION IN VITRO; FOLLOW UP; HUMAN; INCIDENCE; INFERTILITY THERAPY; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NIDATION; OVARY POLYCYSTIC DISEASE; OVULATION INDUCTION; PREGNANCY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; TABLET; TREATMENT OUTCOME;

EID: 0034803097     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/16.9.1861     Document Type: Article

References (32)

1. Insulin-like growth factors as intraovarian regulators of granulosa cell growth and function
2. Adjuvant L-arginine treatment for in-vitro fertilization in poor responder patients
3. Dexamethasone and 11-dehydrodexamethasone as tools to investigate the isozymes of 11 beta-hydroxysteroid dehydrogenase in vitro and in vivo
4. The addition of a glucocorticoid to the protocol of programmed oocyte retrieval for in-vitro fertilization - A randomized study
5. MIF as a glucocorticoid-induced modulator of cytokine production
6. Acute administration of glucocorticoids: A new and peculiar stimulus to growth hormone secretion in man
7. Effect of prednisolone on serum and follicular fluid androgen concentrations in women with polycystic ovarian syndrome undergoing in-vitro fertilization
8. Alteration of peripheral IGF-1 concentrations in IVF patients treated with buserelin
9. Characterization of insulin-like growth factor binding to human granulosa cells obtained during in-vitro fertilization
10. Oocyte maturation in mummichog (Fundulus heteroclitus): Effects of steroids on germinal vesicle breakdown of intact follicles
11. Clinical applications of growth hormone for ovarian stimulation
12. Comparison of 'poor' responders with 'good' responders using a standard buserelin/human menopausal gonadotrophin regime for in-vitro fertilization
13. Corticosteroids may act via IGF-1 to improve the response to ovarian stimulation in IVF 'poor' responders
14. Insulin-like growth factors and their binding proteins: Biological actions
15. Assisted conception following poor ovarian response to gonadotrophin stimulation
16. Could ovarian infection impair the ovarian response to gonadotrophin stimulation?
17. The relation between IgG antibodies to Chlamydia trachomatis and poor ovarian response to gonadotrophin stimulation before in-vitro fertilization
18. Prednisolone supplementation to Clomid and/or gonadotrophin stimulation for in-vitro fertilization - A prospective randomized trial
19. Pyridostigmine cotreatment for controlled ovarian hyperstimulation in low responders undergoing in-vitro fertilization-embryo transfer
20. High-dose human menopausal gonadotropin stimulation in poor responders does not improve in-vitro fertilization outcome
21. Analysis of the suppression of IL-1 alpha and IL-1 beta production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone
22. The possible role of the immune system in the aetiopathogenesis of ovarian hyperstimulation syndrome
23. The effects of dexamethasone treatment on immunoreactive and bioactive insulin-like growth factors (IGFs) and IGF-binding proteins in normal male volunteers
24. Improvement of clinical pregnancy rate and implantation rate of in-vitro fertilization-embryo transfer patients by using methylprednisolone
25. Polycystic ovaries a common finding in normal women
26. Endogenous plasma growth hormone and the occurrence of pregnancies in patients undergoing in-vitro fertilization and embryo transfer with ovarian stimulation
27. The glucocorticoid response element II is functionally homologous in rat and human insulin-like growth factor-binding protein-1 promoters
28. The detection and confirmation of 11β-hydroxysteroid dehydrogenase type 1 transcripts in human luteinized granulosa cells using RT-PCR and plasmid pUC18
29. Periovulatory human oocytes, cumulus cells and ovarian leukocytes express type 1 but not type 2 11-beta-hydroxysteroid dehydrogenase (11 β-HSD) RNA
30. Ovarian responses to menopausal gonadotrophins in groups of patients with differing basal growth hormone levels
31. Differential expression of messenger ribonucleic acids encoding 11β-hydroxysteroid dehydrogenase types 1 and 2 in human granulosa cells
32. Anatomy of the human ovarian insulin-like growth factor system