Meanderings of the mRNA through the ribosome

Structure

Volumn 9, Issue 9, 2001, Pages 751-758

  Culver, Gloria M ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RIBONUCLEOPROTEIN; RIBOSOME PROTEIN; RIBOSOME RNA; RNA 16S; TRANSFER RNA;

AMINO ACID SEQUENCE; ANTICODON; ARTICLE; BINDING SITE; CELL STRUCTURE; CHROMOSOME TRANSLOCATION; CODON; CODON USAGE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; RIBOSOMAL FRAMESHIFTING; RIBOSOME; RIBOSOME SUBUNIT; RNA BINDING; RNA TRANSLATION; START CODON; TRANSLATION INITIATION; TRANSLATION REGULATION; X RAY CRYSTALLOGRAPHY;

EID: 0034802614     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00649-9     Document Type: Review

References (52)

1. tRNA-ribosome interactions
2. Ribosome fidelity: tRNA discrimination, proofreading and induced fit
3. The path of the messenger RNA through the ribosome
4. How does the mRNA pass through the ribosome?
5. A model of the translational apparatus based on three-dimensional reconstruction of the E. coli ribosome
6. The 3′-terminal sequence of Escherichia coli 16S ribosomal RNA: Complementarity to nonsense triplets and ribosome binding sites
7. Initiation of translation in prokaryotes and eukaryotes
8. Crystal structure of the ribosome at 5.5 A resolution
9. Structure of the 30S ribosomal subunit
10. Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution
11. The complete atomic structure of the large ribosomal subunit at 2.4 A resolution
12. X-ray crystal structures of 70S ribosome functional complexes
13. Crystal structure of an initiation factor bound to the 30S ribosomal subunit
14. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
15. The structural basis of ribosome activity in peptide bond synthesis
16. Recognition of cognate transfer RNA by the 30S ribosomal subunit
17. Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
18. Ribosome structure: Localization of 3′ end of RNA in small subunit by immunoelectronmicroscopy
19. Localization of the 3′ end of Escherichia coli 16 S RNA by electron microscopy of antibody-labelled subunits
20. Template-free ribosomal synthesis of polylysine from lysyl-tRNA
21. Template-free ribosomal synthesis of polypeptides from aminoacyl-tRNA. Polyphenylalanine synthesis from phenylalanyl-tRNALys
22. The location of mRNA in the ribosomal 30S initiation complex; site-directed cross-linking of mRNA analogues carrying several photo-reactive labels simultaneously on either side of the AUG start codon
23. Site-directed cross-linking of mRNA analogues to the Escherichia coli ribosome; identification of 30S ribosomal components that can be cross-linked to the mRNA at various points 5′ with respect to the decoding site
24. Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes
25. Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA
26. Identification of bases in 16S rRNA essential for tRNA binding at the 30S ribosomal P site
27. Three-dimensional reconstruction of the Escherichia coli 30S ribosomal subunit on ice
28. Conservation of primary structure in 16S ribosomal RNA
29. Interconversion of active and inactive 30 S ribosomal subunits is accompanied by a conformational change in the decoding region of 16 S rRNA
30. Dominant lethal mutations in a conserved loop in 16S rRNA
31. A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA
32. Mapping of chloroplast mutations conferring resistance to antibiotics in Chlamydomonas: Evidence for a novel site of streptomycin resistance in the small subunit rRNA
33. Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: Correlation of genetic and physical maps of the chloroplast genome
34. Substitution of an invariant nucleotide at the base of the highly conserved '530-loop' of 15S rRNA causes suppression of yeast mitochondrial ochre mutations
35. Evidence for functional interaction between elongation factor Tu and 16S ribosomal RNA
36. Fidelity of amino-acyl-tRNA selection on the ribosome: Kinetic and structural mechanisms
37. Structure and function of ribosomes and their molecular components
38. Identification and functional characterization of the protein controlled by the streptomycin-resistant locus in E. coli
39. Altered ribosomal protein in streptomycin- dependent Escherichia coli
40. Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation
41. Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy
42. Structure of a bacterial 30S ribosomal subunit at 5.5 Å resolution
43. Direct translation of a circular messenger DNA
44. Interaction of antibiotics with functional sites in 16S ribosomal RNA
45. Base complementarity in helix 2 of the central pseudoknot in 16S rRNA is essential for ribosome functioning
46. A cold-sensitive mutation in 16S rRNA provides evidence for helical switching in ribosome assembly
47. A ribosomal ambiguity mutation
48. Effect of Mg2+ concentration, polyamines, streptomycin, and mutations in ribosomal proteins on the accuracy of the two-step selection of aminoacyl-tRNAs in protein biosynthesis
49. Ram ribosomes are defective proofreaders
50. A role for proteins S3 and S14 in the 30 S ribosomal subunit
51. Structure, stability and function of RNA pseudoknots involved in stimulating ribosomal frameshifting
52. Ribbons