Two-dimensional gel analysis of secreted proteins induced by interleukin-1β in rat astrocytes

Neurochemistry International

Volumn 39, Issue 5-6, 2001, Pages 349-359

  Chang, Julia W ^a   Young, Donald A ^a   Coleman, Paul D ^a   O'Banion, M Kerry ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Alzheimer's disease; Basic fibroblast growth factor; C3 complement component; Ceruloplasmin; CNS injury; Plasminogen activator inhibitor type 1; Tumor necrosis factor ; Two dimensional gel electrophoresis

Indexed keywords

CELL PROTEIN; CERULOPLASMIN; COMPLEMENT COMPONENT C3; FIBROBLAST GROWTH FACTOR; INTERLEUKIN 1BETA; PLASMINOGEN ACTIVATOR INHIBITOR 1; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CELL SECRETION; CONTROLLED STUDY; DRUG MECHANISM; GEL ELECTROPHORESIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN INDUCTION; PROTEIN SECRETION; RAT;

ANIMALS; ASTROCYTES; CELLS, CULTURED; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FIBROBLAST GROWTH FACTOR 2; HUMANS; INTERLEUKIN-1; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034802595     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(01)00042-0     Document Type: Article

References (69)

1. Basic FGF in astroglial, microglial, and neuronal cultures: Characterization of binding sites and modulation of release by lymphokines and trophic factors
2. Interleukin-1 binding sites on astrocytes
3. Basic FGF in astroglial, microglial, and neuronal cultures: Characterization of binding sites and modulation of release by lymphokines and trophic factors
4. Interleukin-1 binding sites on astrocytes
5. Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway
6. Differential regulation of C3 gene expression in human astroglioma cells by interferon-gamma and interleukin-1 beta
7. Interleukin-1 and tumor necrosis factor-mediated regulation of C3 gene expression in human astroglioma cells
8. Induction and regulation of interleukin-6 gene expression in rat astrocytes
9. Overexpression of nerve growth factor and basic fibroblast growth factor in AIDS dementia complex
10. Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor beta 1
11. Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1
12. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
13. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
14. Basic fibroblast growth factor (bFGF) injection activates the glial reaction in the injured adult rat brain
15. Complement C1q and C3 mRNA expression in frontal cortex of Alzheimer's patients
16. Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro
17. Astrocytes and microglial cells as immune regulatory cells of the brain
18. Expression of the complement classical pathway by human glioma in culture
19. Interleukin-1 stimulation of astroglial proliferation after brain injury
20. Immunoregulation of cells within the central nervous system
21. Interleukin-1 of the central nervous system is produced by ameboid microglia
22. Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization
23. Interleukin-1 is an astroglial growth factor in the developing brain
24. Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells
25. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
26. Association of early-onset Alzheimer's disease with an interleukin-1 alpha gene polymorphism
27. Recombinant interleukin-1β stimulates eicosanoid production in rat primary culture astrocytes
28. Interferon-γ and interleukin 1β induce nitric oxide formation from primary mouse astrocytes
29. Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain
30. 2 in rat astrocyte cultures: Modulatory effect of neuropeptides
31. Ceruloplasmin gene expression in the murine central nervous system
32. Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ
33. Growth factor- and dexamethasone-induced proteins in Swiss 3T3 cells: Relationship to DNA synthesis
34. Increased regional concentrations of ceruloplasmin in neurodegenerative disorders
35. A specific histochemical marker (lectin Ricinus communis agglutinin-1) for normal human microglia, and application to routine histopathology
36. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
37. Tumor necrosis factor alpha, interleukin 1 and related cytokines in brain development: Normal and pathological
38. Induction of interleukin-1 mRNA in rat brain transient forebrain ischaemia
39. Interleukin-1 activates transcription factor NFκB in glial cells
40. Interleukin-1 and the immunogenetics of Alzheimer disease
41. Inflammation and Alzheimer's disease
42. Association of interleukin-1 gene polymorphisms with Alzheimer's disease
43. A serum- and glucocorticoid-regulated 4 kb mRNA encodes a cyclooxygenase related protein
44. Interleukin-1β induction of prostaglandin G/H synthase-2 (PGHS-2) and inducible nitric oxide synthase (iNOS) in cultured murine glial cells
45. Interleukin-1β induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures
46. Effects of interleukin-1β and tumor necrosis factor-α on the expression of glial fibrillary acidic protein and transferrin in cultured astroctyes
47. Expression of ceruloplasmin by astrocytes and its modulation by cytokines
48. A novel glycosylphosphatidylinositol-anchored form of ceruloplasmin is expressed by mammalian astrocytes
49. Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis
50. Interleukin-1 beta increases basic fibroblast growth factor mRNA expression in adult rat brain and organotypic hippocampal cultures
51. Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3
52. Enhanced release of plasminogen activator inhibitor(s) but not plasminogen activators by cultured rat glial cells treated with interleukin-1
53. Annual review prize lecture: Cytokines - Killers in the brain?
54. Ran-2, a glial lineage marker, is a GPI-anchored form of ceruloplasmin
55. Induction of nitric oxide sythase in glial cells
56. Roles for protein kinases in the induction of nitric oxide synthase in astrocytes
57. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion
58. Regulation of plasminogen activator inhibitor-1 mRNA accumulation by basic fibroblast growth factor and transforming growth factor-beta 1 in cultured rat astrocytes
59. Cytokine expression in the brain during the acquired immunodeficiency syndrome
60. Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors
61. Plasminogen activator inhibitor-1: A common denominator in cardiovascular disease
62. Mechanism of nerve growth factor messenger RNA regulation by interleukin-1 and basic fibroblast growth factor in primary cultures of rat astrocytes
63. IL1 and TNFα induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway
64. The role of copper in neurodegenerative disease
65. Complement gene expression in human brain: Comparison between normal and Alzheimer disease cases
66. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia
67. γ-Interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo
68. Cytokine regulation of nerve growth factor-mediated cholinergic neurotrophic activity synthesized by astrocytes and fibroblasts
69. Very-high-resolution two-dimensional electrophoretic separation of proteins on giant gels