A reporter gene assay for the detection of phytoestrogens in traditional Chinese medicine

Phytotherapy Research

Volumn 15, Issue 6, 2001, Pages 487-492

  Miller Martini, D M ^a   Chan, R Y K ^a   Ip, N Y ^a   Sheu, S J ^b   Wong, Y H ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

Author keywords

Bupleurum Peony Formula; Menopausal syndrome; Oestrogen receptor; Phytoestrogen; Reporter gene; Traditional Chinese medicine (TCM)

Indexed keywords

BUPLEURUM ROOT; PAEONIA EXTRACT; PHYTOESTROGEN;

ARTICLE; BIOLUMINESCENCE; CHINESE MEDICINE; CLINICAL PROTOCOL; CONTROLLED STUDY; DRUG DETERMINATION; HUMAN; HUMAN CELL; MENOPAUSAL SYNDROME; REPORTER GENE; STANDARDIZATION;

BUPLEURUM; PAEONIA;

EID: 0034801160     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.767     Document Type: Article

References (36)

1. Assessing the estrogenic and dioxin-like activities of chemicals and complex mixtures using in vitro recombinant receptor-reporter gene assays
2. Phenol red in tissue culture media is a weak estrogen: Iimplications concerning the study of estrogen-responsive cells in culture
3. Estrogen receptors in human nontarget tissues: Biological and clinical implications
4. Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro
5. Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro
6. The steroid and thyroid hormone receptor superfamily
7. T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance
8. Universal assay of vitellogenin as a biomarker for environmental estrogens
9. Steroid receptor analyses of nine human breast cancer cell lines
10. Oestrogenic activity of tamoxifen and its metabolites on gene regulation and cell proliferation in MCF-7 breast cancer cells
11. Differential responsiveness of human breast cancer cell lines MCF-7 and T47D to growth factors and 17 beta-estradiol
12. Anti-estrogen activity in the yeast transcription system: Estrogen receptor mediated agonist response
13. Functional domains of the human estrogen receptor
14. Temporal relationships between hormone receptor binding and biological responses in the uterus: Studies with short- and long-acting derivatives of estradiol
15. Uterine peroxidase as a marker for estrogen action
16. Validation of two in vitro test systems for estrogenic activities with zearalenone, phytoestrogens and cereal extracts
17. Progesterone and estradiol interaction in the regulation of rat uterine weight and estrogen receptor concentration
18. Commonly occurring plant flavonoids have estrogenic activity
19. Estrogenic flavonoids: Structural requirements for biological activity
20. Two new antiepilepsy compounds: Otophyllosides A and B
21. Serum regulation of the estrogen responsiveness of the human breast cancer cell line MCF-7
22. Functional analysis of the human estrogen receptor using a phenotypic transactivation assay in yeast
23. Synergistic activation of transcription by the human estrogen receptor bound to tandem responsive elements
24. Assessment of the estrogenic activity of phytoestrogens isolated from bourbon and beer
25. Variants of the human prostate LNCaP cell line as tools to study discrete components of the androgen-mediated proliferate response
26. Phytoestrogen intake and prostate cancer: A case-control study using a new database
27. Mouse lactoferrin gene: A marker for estrogen and epidermal growth factor
28. The limits of the cellular capacity to mediate an estrogen response
29. Characterization and implications of estrogenic down-regulation of human catechol-O-methyltransferase gene transcription
30. In vitro bioassays for assessing estrogenic substances
31. Detection of estrogen- and dioxin- like activity in pulp and paper mill black liquor and effluent using in vitro recombinant receptor/reporter gene assays
32. Selective uptake of estrogenic compounds by Saccharomyces cerevisiae: A mechanism for antiestrogen resistance in yeast expressing the mammalian estrogen receptor