Conserved cardiogenic functions of the multitype zinc-finger proteins: U-shaped and FOG-2

Trends in Cardiovascular Medicine

Volumn 11, Issue 5, 2001, Pages 185-190

  Fossett, Nancy ^b   Schulz, Robert A ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR; ISOPROTEIN; PROTEIN FOG 2; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

CELL FATE; CELL MIGRATION; CORONARY BLOOD VESSEL; DROSOPHILA; EUKARYOTE; GENE ACTIVATION; GENETIC TRANSCRIPTION; HEART DEVELOPMENT; HEART MUSCLE; IN VITRO STUDY; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0034800258     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(01)00092-5     Document Type: Review

References (36)

1. Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages
2. U-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila
3. FOG acts as a repressor of red blood cell development in Xenopus
4. The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
5. The multitype zinc-finger protein U-shaped functions in heart cell specification in the Drosophila embryo
6. Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers
7. Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo
8. The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila
9. D-mef2 is a target for Tinman activation during Drosophila heart development
10. Different contributions of pannier and wingless to the patterning of the dorsal mesothorax of Drosophila
11. Heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo
12. Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila
13. hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation
14. The transcription factor GATA6 is essential for early extraembryonic development
15. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
16. The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression
17. Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions
18. FOG-2, a heart- and brain-enriched cofactor for GATA transcription factors
19. A class of zinc fingers involved in protein-protein interactions biophysical characterization of CCHC fingers from fog and U-shaped
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22. Development of the hematopoietic system
23. Embryonic stem cells and transgenic mice in the study of hematopoiesis
24. GATA transcription factors and cardiac development
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26. Gata5 is required for the development of the heart and endoderm in zebrafish
27. GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: Role for regulating early cardiac gene expression
28. Requirements of DFR1/Heartless, a mesoderm-specific Drosophila FGF-receptor, for the formation of heart, visceral and somatic muscles, and ensheathing of longitudinal axon tracts in CNS
29. A functionally conserved N-terminal domain of the Friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription
30. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2
31. Molecular cloning of FOG-2: A modulator of transcription factor GATA-4 in cardiomyocytes
32. FOG-2: A novel Gata-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped
33. FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium
34. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
35. Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators