The effect of pedigree complexity on quantitative trait linkage analysis

Genetic Epidemiology

Volumn 21, Issue SUPPL. 1, 2001, Pages

  Dyer, T D ^a   Blangero, J ^a   Williams, J T ^a   Goring H H H ^a   Mahaney, M C ^a  

^a SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Expected LOD score; Inbred pedigree; Power; Statistical genetics; Variance components

Indexed keywords

IMMUNOGLOBULIN E;

ANALYTIC METHOD; CONFERENCE PAPER; GENE LOCUS; GENETIC LINKAGE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; INBREEDING; MAJOR CLINICAL STUDY; PEDIGREE; POPULATION; QUANTITATIVE TRAIT; STATISTICAL MODEL; SYSTEM ANALYSIS; VARIANCE;

EID: 0034798151     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.2001.21.s1.s236     Document Type: Conference Paper

References (10)

1. Estimation of variance components of quantitative traits in inbred populations
2. Multipoint quantitative-trait linkage analysis in general pedigrees
3. Using risk calculation to implement an extended relative pair analysis
4. Generating consistent genotypic configurations for multi-allelic loci and large complex pedigrees
5. Homozygosity mapping: A way to map human recessive traits with the DNA of inbred children
6. Genetics of atherosclerosis risk factors in Mexican Americans
7. Genome-wide search for asthma susceptibility loci in a founder population. The collaborative study on the genetics of asthma
8. A pedigree partitioning approach to quantitative trait loci mapping of IgE serum level in the GAW 12 Hutterite data
9. Power of variance component linkage analysis to detect quantitative trait loci