Effects of propofol on mitochondrial function and intracellular calcium shift in bovine aortic endothelial model

Acta Anaesthesiologica Sinica

Volumn 39, Issue 3, 2001, Pages 115-122

  Chang, H C ^a   Tsai, S Y ^a   Wu, G J ^a   Lin, Y H ^a   Chen, R M ^a   Chen, T L ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Calcium; Endothelium; Mitochondria; Propofol

Indexed keywords

3,3' DIHEXYLOXACARBOCYANINE; CALCIUM; CALCIUM IONOPHORE; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; FLUORESCENT DYE; NITROSAMINE; PROPOFOL;

ANESTHESIA INDUCTION; ANIMAL CELL; AORTA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CATTLE; CELL CULTURE; CELL FUNCTION; CLINICAL PRACTICE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; FLUORESCENCE SPECTROSCOPY; HYPOTENSION; MEMBRANE POTENTIAL; MITOCHONDRION; MORPHOLOGY; NONHUMAN; VASCULAR ENDOTHELIUM;

ANESTHETICS, INTRAVENOUS; ANIMALS; AORTA; CALCIUM; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; MEMBRANE POTENTIALS; MITOCHONDRIA; PROPOFOL;

EID: 0034798078     PISSN: 02541319     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Hemodynamic effects of the infusion of the emulsion formulation of propofol during nitrous oxide anesthesia in human
2. Vascular effects of propofol: Smooth muscle relaxation in isolated vein and arteries
3. Human cytochrome P450 monooxygenase system is suppressed by propofol
4. Effects of propofol on functional activities of hepatic and extrahepatic conjugation enzyme systems
5. Propofol inhibits renal cytochrome P450 activity and enflurane defluorination in vitro in hamsters
6. Modulation of cytochrome P-450 dependent monooxygenases in streptozotocin-induced diabetic hamster: I. Effects of propofol on defluorination and cytochrome P-450 activities
7. 2+ channel blocker
8. Study of propofol in bovine aortic endothelium: I. Inhibitory effect on bradykinin-induced intracellular calcium immobilization
9. Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals
10. Influence of the anesthetic 2,6-diisopropylphenol on the oxidative phosphorylation of isolated rat liver mitochondria
11. Uncoupling effect of the general anesthetic 2,6-diisopropylphenol in isolated rat liver mitochondria
12. Spermine inhibition of the permeability transition of isolated rat liver mitochondria: An investigation of mechanism
13. 3 receptor in endothelial cells
14. A digitized fluorescence imaging study of intracellular free calcium, mitochondrial integrity and cytotoxicity in rat renal cells exposed to ionomycin, a calcium ionophore
15. Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis
16. Calcium signaling in endothelial cells stimulated by bradykinin: Calcium measurement in the mitochondria and the cytosol by confocal microscope
17. A rapid method for the evaluation of compounds with mitochondria-protective properties
18. Mechanism of the negative inotropic effect of propofol in isolated ferret ventricular myocardium
19. Propofol induces changes in the cytosolic free calcium concentration and the cytoskeletal organization of cultured human glial cells and primary embryonic rat brain cells
20. Influence of the anesthetic 2,6-diisopropylphenol (propofol) on isolated rat heart mitochondria
21. Effects of the anesthetic propofol on the calcium-induced permeability transition of the rat heart mitochondria: Direct pore inhibition and shift of the gating potential
22. Inositol phosphates and cell signaling
23. Propofol regulation of calcium entry pathways in cultured A10 and rat aortic smooth muscle cells
24. Changes in mitochondrial function induced in isolated guinea-pig ventricular myocyte by calcium overload
25. Cyclosporin inhibits mitochondrial calcium efflux in isolated adult rat ventricular cardiomyocytes
26. 14C-propofol after intravenous dosing to rat, dog and rabbit
27. Pharmacokinetic implications for the clinical use of propofol