The use of sequential designs in genome scans for asthma susceptibility loci with affected sib pairs

Genetic Epidemiology

Volumn 21, Issue SUPPL. 1, 2001, Pages

  Boddeker I R ^a   Muller H H ^a   Kress R ^a   Geller, F ^a   Ziegler, A ^a   Schafer H ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Affected sib pair; Sequential study design; Two stage design

Indexed keywords

ASTHMA; CHROMOSOME 1; CHROMOSOME 6; CHROMOSOME 9; CONFERENCE PAPER; DATA ANALYSIS; FAMILIAL INCIDENCE; GENE LOCUS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HUMAN; SIBLING;

EID: 0034797720     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.2001.21.s1.s49     Document Type: Conference Paper

References (11)

1. Repeated significance tests on accumulating data
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4. Two-stage global search designs for linkage analysis I: Use of the mean statistic for affected sib pairs
5. Discrete sequential boundaries for clinical trials
6. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
7. Significance levels in complex inheritance
8. Optimization of testing times and critical values in sequential equivalence testing
9. Linkage strategies for genetically complex traits. II. The power of affected relative pairs
10. A genome-wide search for linkage to asthma