Vitamin E correlates inversely with non-transferrin-bound iron in sickle cell disease

British Journal of Haematology

Volumn 114, Issue 4, 2001, Pages 917-919

  Marwah, S S ^a   Wheelwright, D ^a   Blann, A D ^a   Rea, C ^a   Beresford, R ^a   Phillips, J D ^b   Wright, J ^a   Bareford, D ^a  

^a CITY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

Author keywords

Antioxidant activity; NTBI; Sickle cell disease; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; BLEOMYCIN; IRON; NON TRANSFERRIN BOUND IRON; TRANSFERRIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IRON BLOOD LEVEL; IRON OVERLOAD; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; SICKLE CELL ANEMIA; TRANSFERRIN BLOOD LEVEL; TRANSFUSION; VITAMIN BLOOD LEVEL;

ADULT; ANEMIA, SICKLE CELL; ANTIOXIDANTS; BLOOD TRANSFUSION; CASE-CONTROL STUDIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; IRON; MALE; STATISTICS, NONPARAMETRIC; TRANSFERRIN; VITAMIN E;

EID: 0034797328     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.03018.x     Document Type: Article

References (12)

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2. Role of bilirubin in the regulation of the penayl radical trapping antioxidant activity of plasma in sickle cell disease
3. Plasma levels of antioxidant vitamins in relation to ischaemic heart disease and cancer
4. Iron complexes and their reactivity in bleomycin assay for radical-promoting loosely bound iron
5. Spontaneous oxygen radical generation by sickle erythrocytes
6. Vitamin E and membrane abnormalities in red cells of sickle cell disease patients and new born infants
7. The role of oxygen radicals in human disease with particular reference to the vascular system
8. Oxidative stress and antioxidant status in beta thalassaemia overload and depletion of lipid soluble antioxidants
9. Membrane damage due to lipid peroxidation
10. Detection, characterisation and bioavailability of membrane associated iron in the intact sickle red cells
11. The effect of a-Tocopherol as an antioxidant on the oxidation of membrane protein thiols induced by free radicals generation in different sites
12. Free Antioxidant status and lipid peroxidation in hereditary haemochromatosis