Quitting cigarette smoking produces minimal loss of chronic tolerance to nicotine

Psychopharmacology

Volumn 158, Issue 1, 2001, Pages 7-17

  Perkins, K A ^a   Gerlach, D ^a   Broge, M ^a   Sanders, M ^a   Grobe, J ^a   Fonte, C ^a   Cherry, C ^a   Wilson, A ^a   Jacob, R ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiovascular; Chronic tolerance; Nicotine; Performance effect; Reinforcement; Smoking cessation; Subjective effect; Tobacco dependence

Indexed keywords

NICOTINE; PLACEBO;

ADULT; ARTICLE; BEHAVIOR; CARDIOVASCULAR EFFECT; CIGARETTE SMOKING; CONTROLLED STUDY; FEMALE; HUMAN; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; PERFORMANCE; PRIORITY JOURNAL; REINFORCEMENT; RELAPSE; SMOKING CESSATION; ABSTINENCE; DRUG CROSS TOLERANCE; HUMAN EXPERIMENT; NORMAL HUMAN; SELF MEDICATION; SEX DIFFERENCE; TASK PERFORMANCE; TIME;

ADMINISTRATION, INTRANASAL; ADULT; ANALYSIS OF VARIANCE; DRUG TOLERANCE; FEMALE; HUMANS; MALE; NICOTINE; PROSPECTIVE STUDIES; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION; SMOKING CESSATION;

EID: 0034794827     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100850     Document Type: Article

References (43)

1. Divergent tolerance to metabolic and cardiovascular effects of nicotine in smokers with low and high levels of cigarette consumption
2. Opioid physical dependence development: Effects of single versus repeated morphine pretreatments and of subjects' opioid exposure history
3. Post-cessation cigarette use: The process of smoking relapse
4. 3] nicotine binding in human postmortem brain
5. Experimental model of smoking re-exposure: Effects on relapse
6. Nicotine tolerance: An analysis of the time course of its development and loss in the rat
7. Response to smoking as a function of prior smoking amounts
8. Nicotine pharmacokinetics and its application to intake from smoking
9. Mood and physiological effects of subcutaneous nicotine in smokers and never-smokers
10. Importance of environmental distractors in the effects of nicotine on short-term memory
11. The Fagerstrom test for nicotine dependence: A revision of the fagerstrom tolerance questionnaire
12. Smoking history, instructions and the effects of nicotine: Two pilot studies
13. Symptoms of tobacco withdrawal
14. Smoking cessation among self-quitters
15. Do former smokers respond to nicotine differently from never smokers? A pilot study
16. Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids
17. Methods for the study of tolerance
18. Effects of chronic nicotine treatment on expression of diverse nicotinic acetylcholine receptor subtypes. I. Dose- and time-dependent effects of nicotine treatment
19. Influence of tobacco abstinence on the disposition kinetics and effects of nicotine
20. Time course study of the effects of chronic nicotine infusion on drug response and brain receptors
21. Downregulation of nicotinic receptor function after chronic nicotine infusion
22. Mecamylamine blocks the development of tolerance to nicotine in rats: Implications for the mechanisms of tolerance
23. Nicotine intake in young smokers: Longitudinal study of saliva cotinine concentrations
24. Smoking habits in relapsed subjects from a smoking cessation trial after one year
25. Classification and assessment of smoking behavior
26. Chronic and acute tolerance to subjective effects of nicotine
27. Chronic and acute tolerance to subjective, behavioral, and cardiovascular effects of nicotine in humans
28. Comparison of acute subjective and heart rate effects of nicotine intake via tobacco smoking vs. nasal spray
29. Acute tolerance to nicotine in smokers: Lack of dissipation within two hours
30. Nicotine preference in smokers as a function of smoking abstinence
31. Greater sensitivity to subjective effects of nicotine in non-smokers high in sensation-seeking
32. Dissociation of nicotine tolerance from tobacco dependence
33. Individual differences in sensitivity to nicotine: Implications for genetic research on nicotine dependence
34. Abstinence effects and reactivity to nicotine during 11 days of smoking deprivation
35. Pharmacodynamic model of tolerance: Application to nicotine
36. Dependence of nicotinic acetylcholine receptor recovery from desensitization on the duration of agonist exposure
37. Nicotine-induced limbic cortical activation in the human brain: A functional MRI study
38. Acute and chronic tolerance to nicotine measured by activity in rats
39. Loss of acute nicotine tolerance and severity of cigarette withdrawal