Granulomatous and cytokine responses to pulmonary Cryptococcus neoformans in two strains of rats

Mycopathologia

Volumn 151, Issue 3, 2001, Pages 121-130

  Kobayashi, M ^a   Ito, M ^a   Sano, K ^a   Koyama, M ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cryptococcus neoformans; Cytokines; Granulomas; Rats

Indexed keywords

CYTOKINE; FUNGAL RNA; MESSENGER RNA;

ANIMAL; ARTICLE; BIOSYNTHESIS; BROWN NORWAY RAT; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LEWIS RAT; LUNG; LUNG GRANULOMA; LUNG MYCOSIS; MALE; METABOLISM; MICROBIOLOGY; NONPARAMETRIC TEST; PATHOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TH1 CELL; TH2 CELL;

ANIMALS; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; CYTOKINES; GRANULOMA, RESPIRATORY TRACT; IMMUNOHISTOCHEMISTRY; LUNG; LUNG DISEASES, FUNGAL; MALE; RATS; RATS, INBRED BN; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, FUNGAL; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; TH1 CELLS; TH2 CELLS;

EID: 0034793456     PISSN: 0301486X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1017900604050     Document Type: Article

References (23)

1. Intravascular granuloma induced by intravenous inoculation of Cryptococcus neoformans
2. Afferent phase production of TNF-α is required for the development of protective T cell immunity to Cryptococcus neoformans
3. Phagocytosis of Cryptococcus neoformans by alveolar macrophages
4. Localization on encapsulated Cryptococcus neoformans of serum components opsonic for phagocytosis by macrophages and neutrophils
5. Effect of granulocyte-macrophage colony-stimulating factor on rat alveolar macrophage anticryptococcal activity in vitro
6. Fungicidal activity of IFN-γ-activated macrophages: Extracellular killing of Cryptococcus neoformans
7. The granulomatous inflammatory response: A review
8. The Th1/Th2 paradigm and experimental murine leishmaniasis
9. Cytokine function during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation: Local and regional participation of IFN-γ, IL-10, and TNF
10. In vivo regulation of macrophage IL-12 production during type 1 and type 2 cytokine-mediated granuloma formation
11. Mycobacterial and schistosomal antigen-elicited granuloma formation in IFN-γ and IL-4 knockout mice
12. Type 1 and type 2 cytokines: From basic science to fungal infections
13. Effect of in vivo rapamycin treatment on de novo T-cell development in relation to induction of autoimmune-like immunopathology in the rat
14. Experimental autoimmune myasthenia gravis may occur in the context of a polarized Th1- or Th2-type immune response in rats
15. - T helper cells
16. Differences in coughing and other responses to intrabronchial infection with Bordetella pertussis among strains of rats
17. Interferon-γ activates rat alveolar macrophages for anticryptococcal activity
18. Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans
19. Early cytokine production in pulmonary Cryptococcus neoformans infections distinguishes susceptible and resistant mice
20. IL-12 and IFN-γ are required for initiating the protective Th1 response to pulmonary cryptococcosis in resistant C.B-17 mice
21. Decreased expression of Th2 type cytokine mRNA contributes to the lack of allergic bronchial inflammation in aged rats
22. Eosinophil-Cryptococcus neoformans interactions in vivo and in vitro