Model-free linkage analysis: Performance under real-world conditions

Genetic Epidemiology

Volumn 21, Issue SUPPL. 1, 2001, Pages

  Barmada, M M ^a   O'Connell, J R ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

MMLS; Mod scores; Model free linkage analysis; NPL scores

Indexed keywords

ANALYTIC METHOD; CHROMOSOME 6; CONFERENCE PAPER; DISEASE MODEL; GENE LOCUS; GENETIC LINKAGE; GENETIC MODEL; MAJOR GENE; MARKER GENE; SCORING SYSTEM; SIMULATION;

EID: 0034793253     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.2001.21.s1.s498     Document Type: Conference Paper

References (13)

1. Direct power comparisons between simple LOD scores and NPL scores for linkage analysis in complex diseases
2. Effects of misspecifying genetic parameters in LOD score analysis
3. The power to detect linkage in complex disease by means of simple LOD-score analyses
4. Fast multipoint linkage calculation with Allegro
5. Lods, wrods, and mods: The interpretation of lod scores calculated under different models
6. Parametric and nonparametric linkage analysis: A unified multipoint approach
7. Efficient computations in multilocus linkage analysis
8. The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-re-coding and fuzzy inheritance
9. Replication of linkage studies of complex traits: An examination of variation in location estimates
10. Power comparison of parametric and nonparametric linkage tests in small pedigrees
11. Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker-sharing statistics
12. The generalized sib pair IBD distribution: Its use in the detection of linkage
13. A class of tests of linkage using affected pedigree members