Desflurane confers neurologic protection for deep hypothermic circulatory arrest in newborn pigs

Anesthesiology

Volumn 95, Issue 4, 2001, Pages 959-964

  Kurth, C Dean ^a,b   Priestley, Margaret ^a,b   Marc Watzman, H ^a   McCann, John ^a   Golden, Jeff ^b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESFLURANE; FENTANYL; INHALATION ANESTHETIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; HEART ARREST; HEART SURGERY; HEMODYNAMICS; HIPPOCAMPUS; INDUCED HYPOTHERMIA; INTERMETHOD COMPARISON; NERVE INJURY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SWINE; TREATMENT OUTCOME;

EID: 0034791762     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200110000-00027     Document Type: Article

References (32)

1. Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass
2. Postoperative neurologic complications after open heart surgery on young infants
3. Isoflurane neuroprotection
4. Halothane reduces focal ischemie injury in the rat when brain temperature is controlled
5. Differential effects of anesthetic agents on outcome from near-complete but not incomplete global ischemia in the rat
6. Sevoflurane improves neurologic outcome after incomplete cerebral ischaemia in rats
7. Desflurane and isoflurane improve neurological outcome after incomplete cerebral ischaemia in rats
8. Sympathetic ganglionic blockade masks beneficial effect of isoflurane on histologic outcome from near-complete forebrain ischemia in the rat
9. Fentanyl does not increase brain injury after focal cerebral ischemia in rats
10. Isoflurane delays but does not prevent cerebral infarction in rats subjected to focal ischemia
11. Isoflurane reduces N-Methyl-D-Aspartate toxicity in vivo in the rat cerebral cortex
12. Isoflurane and pentobarbital reduce AMPA toxicity in vivo in the rat cerebral cortex
13. Isoflurane reduces ischemia-induced glutamate release in rats subjected to forebrain ischemia
14. Anesthetics and mild hypothermia similarly prevent hippocampal neuron death in an in vitro model of cerebral ischemia
15. Anesthetic effects on cerebral metabolic rate predict histologic outcome from near-complete forebrain isehemia in the rat
16. Desflurane increases brain tissue oxygenation and pH
17. Desflurane animal and human pharmacology: Aspects of kinetics, safety, and MAC
18. Cardiovascular and respiratory actions of desflurane: Is desflurane different from isoflurane?
19. Washin and washout of isoflurane administered via bubble oxygenators during hypothermic cardiopulmonary bypass
20. Regional patterns of neuronal death after deep hypothermic circulatory arrest in newborn pigs
21. Neuroprotective therapy
22. Substantia nigra lesion protects against ischemic damage in the striatum
23. High dose intravenous naloxone for the treatment of acute ischemic stroke
24. Rapid and direct modulation of GABA receptors by halothane
25. Effects of halothane, isoflurane, and sevoflurane on ischcmia-reperfusion injury in the perfused liver of fasted rats
26. Norepinephrine-induced apoptosis is inhibited in adult rat ventricular myocytes exposed to volatile anesthetics
27. Isoflurane preconditions myocardium against infarction via activation of inhibitory guanine nuclcotide binding proteins
28. Isoflurane-sevoflurane administration before ischemia attenuates ischemia-reperfusion-induced injury in isolated lungs
29. 2O on concentrations of brain and plasma catecholamines during near-complete cerebral ischemia in the rat
30. The effects of anesthetics on stress responses to forebrain ischemia and reperfusion in the rat
31. Brain cooling efficiency with alpha-stat and pH-stat cardiopulmonary bypass in newborn pigs
32. Brain caspase activity increases after deep hypothermic circulatory, arrest in newborn pigs